Radioautography in cancer

Fitzgerald, Patrick

doi:10.1002/1097-0142(195201)5:1<166::aid-cncr2820050124>3.0.co;2-q

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No One But Great Hairy Rough Squatters Have Any Business Her1

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1952

1998

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Cited by 16 publications

(2 citation statements)

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“…The ACTH data, nevertheless, tend to support the concept that the label on these hormones does not affect their specificity. It is of interest that radioautographs of renal ACTH-I'8' (9) closely resemble those of insulin-I181.…”

Section: Discussionmentioning

confidence: 99%

Distribution and Degradation Studies with Insulin-I131†

Elgee¹,

Williams²,

Lee³

1954

J. Clin. Invest.

117

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Diabetes mellitus is of obscure etiology, often presenting profound metabolic derangement with a sparsity of morphopathologic change. Insulin reverses many of the metabolic changes, yet its mechanism of action is poorly understood; furthermore, in most patients with diabetes mellitus, the fundamental causes of the insulin insufficiency are not known. An important approach to this challenging problem is the study -of insulin metabolism. Such a study has been hampered by unsatisfactory assay techniques, and, as a-result, very little is known even of the fate of insulin. The use of labeled hormone greatly facilitates such a study, and, in this report, the validity of such an approach is considered, and distribution and degradation studies using I'8l-labeled insulin are described.

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Section: Discussionmentioning

confidence: 99%

Distribution and Degradation Studies with Insulin-I131†

Elgee¹,

Williams²,

Lee³

1954

J. Clin. Invest.

117

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show abstract

“…Two mines at this northem town, at one stage in diis period the second most populous in Queensland, produced 13 per cent of Queensland's gold in 1886. 213 These examples, however, masked a patchy industry.…”

Section: No One But Great Hairy Rough Squatters Have Any Business Hermentioning

confidence: 99%