Radiodermatitis incidents in cancer patients receiving radiotherapy at Haji Adam Malik Central Hospital, Medan-Indonesia

Manik, Monalisa; Yosi, Ariyati; Tanjung, Chairiyah

doi:10.15562/bmj.v7i2.776

Cited by 2 publications

(3 citation statements)

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“…We were, however, not able to demonstrate a significant association of gender with toxicity, which could be inaccurate considering the disproportionate number of women in the study (male-to-female ratio of 4.8:1). Previous studies have failed to establish an association of severe toxicity with gender, with some substantiating it and others contesting [10,11,16,17].…”

Section: Discussionmentioning

confidence: 99%

Factors Influencing the Severity of Acute Radiation-Induced Skin and Mucosal Toxicity in Head and Neck Cancer

Chugh¹,

Bisht²,

Nautiyal³

et al. 2021

Cureus

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Background and purposeRadiotherapy is a crucial part of cancer therapy armamentarium, but it is associated with skin and mucosal toxicity in a substantial proportion of patients with head and neck cancer. Its extent, however, depends on several patient-related and treatment-related factors. In-depth knowledge of these is prudent for better patient management. AimThe aim of this study is to assess the factors influencing the severity of acute radiation-induced skin and mucosal toxicity in patients with head and neck cancer receiving external beam radiotherapy. Materials and methodsThis longitudinal observational study included all patients receiving curative external beam radiotherapy for head and neck cancer aged 18 years or above from January 2018 to December 2018. Patient-related and treatment-related characteristics including age, gender, type, staging and site of cancer, history of smoking and diabetes, surface area exposed, and concurrent chemotherapy were compared in patients experiencing severe and non-severe acute skin and mucosal toxicity using the Radiation Therapy Oncology Group (RTOG) scoring system. ResultsHigher age (p = 0.002), TNM stage IV (p = 0.023), and concurrent administration of chemotherapy (p = 0.002) were statistically associated with severe acute radiation-induced skin and mucosa toxicity, whereas gender, surface area irradiated, history of smoking, and diabetes did not show such an association. ConclusionOlder patients with TNM stage IV malignancy receiving concurrent chemotherapy are at a high risk of developing skin and mucosal toxicity that might interfere with the treatment protocol and warrant hospitalization, compromising their quality of life.

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Section: Discussionmentioning

confidence: 99%

Factors Influencing the Severity of Acute Radiation-Induced Skin and Mucosal Toxicity in Head and Neck Cancer

Chugh¹,

Bisht²,

Nautiyal³

et al. 2021

Cureus

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“…Os fatores relacionados à radioterapia (extrínsecos) são a dose total, fracionamento, volume irradiado, técnica de planejamento do tratamento e tipo de energia. Enquanto os fatores relacionados ao paciente (intrínsecos) referem-se à idade avançada, genética, área tratada, comorbidades (obesidade e diabetes), tabagismo, desnutrição, exposição crônica ao sol, tratamento concomitante com quimioterapia e uso de medicamentos a base de receptor do Fator de Crescimento Epidérmico (Epidermal Growth Factor Receptor -EGFR) (MANIK; YOSI, TANJUNG, 2018;WEI et al, 2019).…”

Section: Kole; Moran 2017)unclassified

“…Os efeitos agudos da radioterapia são normalmente vistos nos tecidos com alta divisão celular, tais como o trato respiratório superior, a mucosa gastrointestinal, a pele e a medula óssea (BENNARDO et al, 2021). Estes efeitos, geralmente, aparecem de duas a três semanas após o início do tratamento, e podem se manter por quatro a sete semanas (MANIK;YOSI;TANJUNG, 2018).…”

Section: Introductionunclassified

Escalas para mensurar radiodermatite aguda: vantagens e desvantagens

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Ferreira

et al. 2022

CONJ

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Avaliar e mensurar a radiodermatite é essencial para o gerenciamento das lesões e para a tomada de decisão de forma correta, baseada em evidências científicas. De modo geral, a radiodermatite é avaliada e graduada por escalas. Este artigo consiste em revisão narrativa da literatura e tem como objetivo descrever conceitos sobre radioterapia e radiodermatite, bem como apresentar as características dos instrumentos de medida disponíveis na literatura para graduar a radiodermatite. Um instrumento bem elaborado e minucioso pode proporcionar consenso da avaliação e continuidade do cuidado ao paciente, além de auxiliar na uniformização da linguagem para o estabelecimento de protocolos assistenciais e de pesquisa. Diante da elevada incidência de radiodermatite entre os pacientes submetidos à radioterapia e das limitações identificadas nos instrumentos de graduação presentes na literatura, fez-se necessária a elaboração de um instrumento que use critérios objetivos e precisos para mensurar a radiodermatite aguda, que inclua a avaliação dos possíveis sintomas relatados pelo paciente.

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Radiodermatitis incidents in cancer patients receiving radiotherapy at Haji Adam Malik Central Hospital, Medan-Indonesia

Cited by 2 publications

References 0 publications

Factors Influencing the Severity of Acute Radiation-Induced Skin and Mucosal Toxicity in Head and Neck Cancer

Factors Influencing the Severity of Acute Radiation-Induced Skin and Mucosal Toxicity in Head and Neck Cancer

Escalas para mensurar radiodermatite aguda: vantagens e desvantagens

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