Radiofrequency Ablation for Eradication of Pulmonary Tumor in Rabbits

Radiological and Pathological Correlation of Lung Malignant Tumors Treated with Percutaneous Radiofrequency Ablation

“…Following RFA an inflammatory response occurs in the area surrounding the tumors due to the local release of high energy. In a radiologic-histopathologic correlation study in rabbits, Miao et al found that increased inflammatory response occurs at the periphery of the lung parenchyma surrounding the tumor 3 days after RFA therapy (14). However, in contrast to what we found, they have not described the presence of residual tumor cells in the lung after RFA.…”

“…In the present study, contrastenhanced CT and magnetic resonance imaging enhanced shadows in the peripheral areas of the tumor. Miao et al have previously demonstrated that enhanced radiological images may be due to the inflammatory response induced by the RFA technical procedure itself at the periphery of the tumor (14). Following RFA an inflammatory response occurs in the area surrounding the tumors due to the local release of high energy.…”

Thermal Ablation of Lung Tumors: Focus on Microwave Ablation

“…The middle layer has a similar appearance as the inner one but the alveolar spaces are filled with effusion and some degree of congestion can be noticed. The outer layer shows strong congestion and hemorrhage and consists of both damaged and viable cells [37,58,59].…”

“…1 -4) [33,55,58,59]. If contrast agent is administered, the outer rim usually shows circular benign periablational enhancement [60].…”

Percutaneous ablation of malignant thoracic tumors

“…Other energy sources are available, including microwave, cryoablation and laser (2,7,10,11). The type of energy that can be used will depend on the patient, location and nature of the tumor, treatment goal, and operator experience or preference.…”