Radiofrequency ablation for the treatment of non–small cell lung cancer in marginal surgical candidates

Abstract

This study demonstrates the feasibility of radiofrequency ablation for small, peripheral non-small cell lung cancer tumors. Local control is comparable to, if not better than, that provided by radiotherapy. Radiofrequency ablation should continue to be evaluated by thoracic surgeons as a noninvasive therapy for the high-risk patient with non-small cell lung cancer.

Percutaneous radiofrequency thermal ablation (rfa) in the management of lung tumors: presentation of clinical experience on a series of 35 patients from a single clinic.

“…Specifically, six studies included patients with NSCLC and metastatic lung disease originating from other primary tumors (9, 12-16), two studies included only patients with colorectal metastases (CRM) (17,18) and four studies included only patients with inoperable NSCLC (19)(20)(21)(22). Of the studies with patients with inoperable NCSLC, two included patients with stage I carcinoma (20,22), whereas in our study the patients with primary lung tumors had stage II-IV disease (15).…”

Value of C-arm computed tomography in radiofrequency ablation of small lung lesions

“…Our research adopted a modified response evaluation criteria for solid tumors (Fernando et al, 2005), which consisted of complete response, partial response, stable disease, and progressive disease, as summarized in Table 1. CT reviews were performed at 1, 3, and 6 months after the operation.…”

The Evolution of VATS Lobectomy

“…For a start, VATS lobectomy can no longer claim to be the least traumatic mode of curative therapy for lung cancer. Today, ablative therapy (using radiofrequency or microwave energy), stereotactic ('cyberknife') radiosurgery, and stereotactic body radiation therapy (SBRT) all have better claims for that title (Fernando et al, 2005;Pennathur et al, 2009;Crabtree et al, 2010). SBRT is now wholly claimed by Oncologists, and there is no guarantee that surgeons will gain control of ablative and cyberknife therapy.…”