Radiofrequency Coagulation of Renal Parenchyma: Comparison of Effects of Energy Generators on Treatment Efficacy

Abstract

Use of a specific RF energy generator with recommended treatment protocols does not appear to affect coagulation of normal renal parenchyma in the porcine model.

Analysis of the effect of renal excretory system cooling during thermal radiofrequency ablation in an animal model

“…Some use a formula to calculate the volume of an ellipse (10), others use only the greatest diameter (11) or both diameters multiplied. We believe that the analysis of the three biggest diameters (longitudinal, anteroposterior and depth), as described by Gettman and Rehman (5,6) is more accurate since allows tridimensional analysis of the lesion.…”

“…The kidneys were removed and opened (convex part) and the biggest dimensions of the lesion were recorded: longitudinal, anteroposterior and depth, using a digital capiler rule as previously proposed (5,6).…”

Image-guided Percutaneous Ablation of Renal Tumors: Outcomes, Technique, and Application in Urologic Practice

“…Similar to cryoablation, the ideal ablation zone for renal tumors treated with RFA is 1 cm beyond the tumor margin based on preoperative CT or MRI. RFA and ablation zone diameter can be monitored using either impedance-or temperature-based generators [19]. Impedance systems indicate tumor ablation when tissue adjacent to the probe(s) demonstrates infinite impedance (Ω).…”

Radiofrequency ablation of renal tumors

“…The primary drawback of this system is that treated areas may not reach a temperature sufficient enough for coagulation necrosis to be attained. Gettman et al [20] compared temperature-based and impedance-based systems in an in vivo porcine setting. They found no significant difference between these systems in the ablation of normal renal parenchyma in a porcine model.…”

“…The previous study was limited, in part, by the fact that vital staining as an objective confirmation of tissue viability or nonviability was not employed; nicotinamide adenine dinucleotide (NADH) staining has been reported to be a sensitive indicator of tissue viability [20]. Subsequent series have employed vital staining techniques, such as NADH staining, to determine tissue viability.…”