Radiographic Analysis of Newly Developed Degenerative Spondylolisthesis in a Mean Twelve-Year Prospective Study

Aono, Kiyoshi; Kobayashi, Tetsuya; Jimbo, Shizuo; Atsuta, Yuji; Matsuno, Takeo

doi:10.1097/brs.0b013e3181cdd1aa

Cited by 81 publications

(52 citation statements)

References 37 publications

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“…The results indicated that the PI was a predisposing factor in the pathogenesis and development of DS [12,13,16], supporting the theory that a greater PI implied a greater SS and as a result of a greater LL. The increased LL resulted in greater shear forces at the lumbosacral junction which may increase the risk of presenting or developing spondylolisthesis.…”

Section: Introductionsupporting

confidence: 63%

“…Spinopelvic sagittal alignment accompanied with biomechanical changes has been demonstrated in previous studies in the pathogenesis and development of lumbar degenerative diseases [12][13][14][15][16][17]24]. Several studies have compared the sagittal spinopelvic alignment in LDD or LDH patients with the asymptomatic volunteers, suggesting that the sagittal profile in these patients was characterized by a straight spine (lower LL and TK), vertical sacrum (lower SS and greater SFD) with an anterior displaced C7 plumb line (greater SVA) [13][14][15].…”

Section: Discussionmentioning

confidence: 71%

“…A series of studies correlated the sagittal alignment with several lumbar degenerative diseases, such as degenerative spondylolisthesis (DS), lumbar disc degeneration (LDD) or lumbar disc herniation (LDH) [12][13][14][15][16][17]. The results indicated that the PI was a predisposing factor in the pathogenesis and development of DS [12,13,16], supporting the theory that a greater PI implied a greater SS and as a result of a greater LL.…”

Section: Introductionmentioning

confidence: 91%

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The characteristics of spinopelvic sagittal alignment in patients with lumbar disc degenerative diseases

et al. 2013

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Purpose A comparative study of the spinopelvic sagittal alignment in patients with lumbar disc degeneration or herniation (LDD/LDH) in normal population was designed to analyse the role of sagittal anatomical parameter (pelvic incidence, PI) and positional parameters in the pathogenesis and development of the disease. Several comparative studies of these patients with asymptomatic controls have been done. However, in previous studies without lumbar MRI, a certain number of asymptomatic LDD patients should have been included in the control group and then impacted on the results. Methods Based on MRI findings, we divided 60 LDD or LDH patients and 110 asymptomatic volunteers into the normal group (NG) and the degeneration group (DG), which was further subdivided into the symptomatic (SDG) and asymptomatic (ADG) subgroups according to patients' symptoms. Standing full spine radiographs were used to measure sagittal parameters, including PI, sacral slope (SS), pelvic tilt (PT), lumbar lordosis (LL), thoracic kyphosis (TK), sagittal vertical axis (SVA), and sacrumbicoxofemoral distance (SFD). Results The PI, SS and LL in DG were significantly lower than NG, while the SVA and SFD were significantly greater (P \ 0.05). PI correlated well with the SS and LL in all subjects. However, the trend lines of SS or LL over PI were downward in DG. PI was similar in SDG and ADG (P = 0.716) but SS and LL were significantly lower and SVA was significantly greater (P \ 0.05).Conclusions PI may play a predisposing role in the pathogenesis of lumbar disc degenerative diseases. The secondary structural and compensatory factors would lead to a straighter spine after disc degenerative change.

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Section: Introductionsupporting

confidence: 63%

Section: Discussionmentioning

confidence: 71%

Section: Introductionmentioning

confidence: 91%

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The characteristics of spinopelvic sagittal alignment in patients with lumbar disc degenerative diseases

et al. 2013

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“…Aono et al [ 20 ] and Barrey et al [ 21 ] have demonstrated that patients with degenerative spondylolisthesis have a higher pelvic incidence than controls. Another study [ 22 ] compared the spinopelvic parameters of patients with isthmic spondylolisthesis and degenerative spondylolisthesis.…”

Section: Axial Pain From Sagittal Imbalancementioning

confidence: 99%

Pain Generators in Spondylolisthesis

Carragee

Stauff

2015

Spondylolisthesis

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“…1 The estimated incidence of DLS is 12.7% with an overall prevalence of 6% that increases between the fifth and eighth decades of life. [2][3][4] For symptomatic patients, the recent Spine Patient Outcomes Research Trial (SPORT) -DLS study has demonstrated that surgical management is superior to conservative care at 2 and 4 years post-intervention. 5,6 From a surgical perspective, since the controlled study by Herkowitz and Kurz 7 demonstrated a high failure rate following decompression (conventional midline laminectomy) alone (D), decompression and fusion (DF) has become the surgical treatment of choice for patients with DLS.…”

mentioning

confidence: 99%

Health-related quality of life following decompression compared to decompression and fusion for degenerative lumbar spondylolisthesis: a Canadian multicentre study

Rampersaud

Fisher

Yee

et al. 2014

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Health-related quality of life following decompression compared to decompression and fusion for degenerative lumbar spondylolisthesis: a Canadian multicentre study Background: Decompression alone (D) is a well-accepted treatment for patients with lumbar spinal stenosis (LSS) causing neurogenic claudication; however, D is controversial in patients with LSS who have degenerative spondylolisthesis (DLS). Our goal was to compare the outcome of anatomy-preserving D with decompression and fusion (DF) for patients with grade I DLS. We compared patients with DLS who had elective primary 1-2 level spinal D at 1 centre with a cohort who had 1-2 level spinal DF at 5 other centres. Methods:Patients followed for at least 2 years were included. Primary analysis included comparison of change in SF-36 physical component summary (PCS) scores and the proportion of patients achieving minimal clinically important difference (MCID) and substantial clinical benefit (SCB). Results:There was no significant difference in baseline SF-36 scores between the groups. The average change in PCS score was 10.4 versus 11.4 (p = 0.61) for the D and DF groups, respectively. Sixty-seven percent of the D group and 71% of the DF group attained MCID, while 64% of both D and DF groups attained SCB. There was no significant difference between D and DF for change in PCS score (p = 0.74) or likelihood of reaching MCID (p = 0.81) or SCB (p = 0.85) after adjusting for other variables. Conclusion:In select patients with DLS, the outcome of D is comparable to DF at a minimum of 2 years.Contexte : La décompression seule est un traitement bien accepté pour la sténose lombaire (SL) causant une claudication neurogène. Son utilisation ne fait cependant pas l'unanimité chez les patients atteints de SL qui souffrent d'un spondylolisthésis dégénératif (SLD). Notre objectif était de comparer l'issue d'une décompression avec préservation anatomique à celle d'une décompression-arthrodèse (DA) chez des patients atteints de SLD de grade 1. Nous avons comparé les patients atteints de SLD ayant subi une décompression élective primaire de niveau 1-2 dans un centre à une cohorte ayant subi une DA de niveau 1-2 effectuée dans 5 autres centres.Méthodes : Nous avons inclus les patients qui ont été suivis pendant au moins 2 ans. L'analyse primaire comportait une comparaison des changements aux scores sommaires pour la composante physique (CP) du questionnaire SF-36 et la proportion de patients ayant obtenu une différence minimale cliniquement importante (DMCI) et en ayant tiré un bienfait clinique substantiel (BCS). Résultats :Il n'y avait pas de différence significative entre les scores SF-36 des 2 groupes au départ. Le changement moyen du score pour la CP a été de 10,4 c. 11,4 (p = 0,61) dans les groupes soumis à la décompression et à la DA, respectivement. Soixante-sept pour cent des patients du groupe soumis à la décompression et 71 % du groupe soumis à la DA ont obtenu une DMCI, tandis que 64 % des 2 groupes ont obtenu un BCS. On n'a noté aucune différence significative entr...

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Radiographic Analysis of Newly Developed Degenerative Spondylolisthesis in a Mean Twelve-Year Prospective Study

Cited by 81 publications

References 37 publications

The characteristics of spinopelvic sagittal alignment in patients with lumbar disc degenerative diseases

The characteristics of spinopelvic sagittal alignment in patients with lumbar disc degenerative diseases

Pain Generators in Spondylolisthesis

Health-related quality of life following decompression compared to decompression and fusion for degenerative lumbar spondylolisthesis: a Canadian multicentre study

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