Radiographic Contrast Media

Golman, Klaes; Holtz, E.; Almén, Torsten

doi:10.1007/978-94-009-3371-2_10

Nephrotoxicity in the Experimental and Clinical Situation 1987

DOI: 10.1007/978-94-009-3371-2_10

|View full text |Cite

Radiographic Contrast Media

Klaes Golman¹,

E. Holtz²,

Torsten Almén³

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1989

1998

Publication Types

Select...

Article2

Relationship

Self Cite1

Independent1

Authors

Journals

Cited by 2 publications

References 75 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Pharmacokineatic Aspects of Measurement of Glomerular Filtration Rate in the Dog: A Review

Heiene

Moe

1998

Veterinary Internal Medicne

107

View full text Add to dashboard Cite

Glomerular filtration rate (GFR) is estimated by means of clearance, defined as the volume of plasma that has been cleared of a particular substance per unit time. Glomerular filtration rate may be estimated by measuring the renal clearance of a filtration marker using data from both urine and plasma or by plasma clearance using only plasma data. Several alternative pharmacokinetic models are used for the calculation of clearance using various filtration markers with slightly different pharmacokinetic properties. The purpose of this article is to discuss how the choice of marker and pharrnacokinetic model may influence estimated GFR values and to elucidate commonly used methods and reported GFR values in the dog.

show abstract

Pharmacokineatic Aspects of Measurement of Glomerular Filtration Rate in the Dog: A Review

Heiene

Moe

1998

Veterinary Internal Medicne

107

View full text Add to dashboard Cite

show abstract

Effect of Diatrizoate on Renal Extraction of Pah in Man

Tidgren¹,

Golman²

1989

Acta Radiol

Self Cite

View full text Add to dashboard Cite

The effect of diatrizoate on the renal extraction of para-amino hippurate (EPAH) was studied in 8 healthy male volunteers. The contrast medium was injected into an antecubital vein and into a renal vein in each individual. A single-injection technique for the determination of EPAH was used and EPAH was measured before and over a period of 30 min after each contrast medium injection. In addition, the renal extraction of diatrizoate was measured simultaneously. Small but significant and similar decreases in EPAH were observed after both antecubital and renal venous administrations of the contrast medium, with a duration of less than 30 min after the injection. The renal extraction ratio for the diatrizoate was 0.20. It is concluded that diatrizoate should not be used before the determination of EPAH, at least not until 30 min after the administration of the contrast medium. The decrease in EPAH caused by diatrizoate seems to be due to a direct tubular depressant effect.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Radiographic Contrast Media

Cited by 2 publications

References 75 publications

Pharmacokineatic Aspects of Measurement of Glomerular Filtration Rate in the Dog: A Review

Pharmacokineatic Aspects of Measurement of Glomerular Filtration Rate in the Dog: A Review

Effect of Diatrizoate on Renal Extraction of Pah in Man

Contact Info

Product

Resources

About