Radiographic evaluation of rheumatoid arthritis by standard reference films

Larsen, Arvi; Dale, Knut; Eek, Morten; Pahle, J

doi:10.1016/s0363-5023(83)80241-x

Cited by 43 publications

(14 citation statements)

References 3 publications

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“…This technique revolutionized the diagnostic procedures in RMDs. In rheumatology, a major breakthrough was the scoring of x-ray changes such as the Larsen score in 1977 28 and the Sharp score in 1985 29 , which was then modified by van der Heijde et al in 1989 30 . These scores enabled the assessment of structural damage for instance in RA and guided the design of many modern trials providing evidence of halting progression by modern treatment.…”

Section: Imaging and Rmdsmentioning

confidence: 99%

Managing rheumatic and musculoskeletal diseases — past, present and future

et al. 2017

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Progress in rheumatology has been remarkable in the last 70 years impacting favourably on quality of life for people with rheumatic and musculoskeletal diseases. Therapeutics have advanced from early developments including the introduction of glucocorticoids, the general use of methotrexate and other disease modifying agents, through to the advent of biologic and recently small molecule JAK-inhibitors. Strategic approaches using such agents also transformed outcomes. Similarly, non-pharmacologic management of RMDs including surgery, physical and occupational therapy have contributed greatly to progress delivered within the multi-disciplinary team. Breakthroughs in pathogenesis understanding, diagnostics, and the use of 'big data' continue to drive the field. Critically, and especially going forward, the patient is at the centre of management strategies and the future research agenda.

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Section: Imaging and Rmdsmentioning

confidence: 99%

Managing rheumatic and musculoskeletal diseases — past, present and future

et al. 2017

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“…This means a stage IV or V according to Larsen's classifi cation [ 7 ] or a stage II according to Simmen and Herren's classifi cation [ 8 ]. We prefer to use Simmen's classifi cation because it highlights the "arthrosis" type 2 stage (Fig.…”

Section: Indications and Contraindicationsmentioning

confidence: 99%

Advances in Total Wrist Arthroplasty

Herzberg

Boeckstyns

2016

Clinical Management of the Rheumatoid Hand, Wrist, and Elbow

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“…Plain radiographs of hands and feet at the beginning of the CsA treatment and at the end of follow-up were compared for the presence of erosions and joint damage (scored according to Larsen's method) [24].…”

Section: Radiological Examinationmentioning

confidence: 99%

The relationship between serum-soluble interleukin-2 receptor and radiological evolution in psoriatic arthritis patients treated with cyclosporin-A

Macchioni

Boiardi

Cremonesi

et al. 1998

Rheumatology International

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Aims of the study to evaluate the radiologically detected progression of joint damage in patients with psoriatic arthritis (PA) treated with cyclosporin-A (CsA) and to look for clinical and/or immunological parameters that might predict outcome. Twenty-four out-patients suffering from active PA entered a 2-year open prospective study on low-dose CsA (starting dose 3 mg/kg/day). Fifteen patients completed the study. Plain radiographs of hands and feet at study entry and at the end of follow-up were compared for the number of eroded joints. Serum-soluble IL-2 receptor (sIL-2R) levels were available in 13/15 patients before CsA therapy, after 6 months and after 2 years. The mean number of eroded joints per patient increased significantly during the study period (P = 0.017). Nine patients had less than two new eroded joints (responders) while the remaining six patients had five or more new eroded joints (non-responders). Serum sIL-2R levels were in the normal range after 6 months and 2 years of CsA treatment in all the responder patients and were above the 95th percentile of the control population in the six non-responders. We did not find any other demographical, clinical, radiological or laboratory parameter predictive of outcome in conclusion. (1) CsA seems to be able to control the 2-year progression of the radiologically measured damage in peripheral joints in 60% of PA patients. (2) A normal serum sIL-2R level after 6 months of therapy seems to have a prognostic value for a good outcome in PA patients treated with CsA.

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Radiographic evaluation of rheumatoid arthritis by standard reference films

Cited by 43 publications

References 3 publications

Managing rheumatic and musculoskeletal diseases — past, present and future

Managing rheumatic and musculoskeletal diseases — past, present and future

Advances in Total Wrist Arthroplasty

The relationship between serum-soluble interleukin-2 receptor and radiological evolution in psoriatic arthritis patients treated with cyclosporin-A

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