Radioisotope Renography in the Assessment of Renal Function in the Newborn

Winter, Chester C.; Elliott, John P.; Grace, Donald A.; Robertson, Alex

doi:10.1016/s0022-5347(17)62484-4

Cited by 6 publications

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“…These they found to be relatively flat as compared with those obtained from older children. Winter et al (1968) on the other hand performed renography in 26 newborn babies with presumed normal kidney function, and found that in 19 the tracings were of normal adult type; 7 showed a prolonged functional and/or excretory phase.…”

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Radioisotope Renography as a Renal Function Test in the Newborn

Kathel¹

1971

Archives of Disease in Childhood

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TechniqueLugol's iodine solution (0 2 ml) (17 3 mg total iodine and 6-6 mg free iodine) is given orally on the night before and on the evening after the test in order to block the possible uptake of any free radioactive iodine by the thyroid. Renography is carried out 1 hours after a feed to obtain a standard level of hydration. The patient is bandaged to a crucifix splint in the prone position, a detector probe is placed over the site of each kidney, and a third is positioned over the left scapular region. The probes are connected to ratemeters and recorders. The meter range employed has been 30 and the paper speed 1 25 cm/minute. Hippuran 125I 0-3 ,uCi/kg is injected rapidly into a scalp vein. For renography in children over 2 years of age we use a dose of 0 25 ,uCi/kg and a meter range of 100. The modification in technique for newbom infants is necessary to obtain sufficient amplitude in the tracing. If necessary, the positions of the kidney probes are readjusted within a few seconds of the start of the test in order to obtain maximum deflection. The renogram tracings last from 10 to 30 minutes. At the conclusion bladder radioactivity is recorded with the baby in the supine position. All recordings reproduced by recorders are from right to left-a convention in the renographic field.The following parameters were measured from renogram curves.(1) The time interval from the injection to the peak of the tracing (Tm). (2) The time interval from the injection to the point where the curve decays to 500, of the maximum (TI). (3) The amplitude of tracing is expressed by radioactive counts per second.The parameters were compared with those obtained

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