Radiologic Evaluation of Small and Indeterminant Renal Masses

Curry, Nancy S.; Bissada, Nabil K.

doi:10.1016/s0094-0143(05)70398-0

Cited by 35 publications

(11 citation statements)

References 54 publications

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“…Furthermore, roughly 20% to 30% of small renal space occupying lesions are indeterminant cysts (Bozniak 2 s and 3 s), which are not ideal thermotherapeutic approaches and can pose increasing challenges for laparoscopic partial nephrectomy. 10 Thus, approximately 40% of newly diagnosed small renal lesions, which represent as many as two-thirds of the newly diagnosed renal tumors, are not always amenable to current minimally invasive nephron-sparing interventions.…”

Section: Introductionmentioning

confidence: 99%

Optical property measurements establish the feasibility of photodynamic therapy as a minimally invasive intervention for tumors of the kidney

et al. 2012

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Abstract. We measured the optical properties of freshly excised kidneys with renal parenchymal tumors to assess the feasibility of photodynamic therapy (PDT) in these patients. Kidneys were collected from 16 patients during surgical nephrectomies. Spatially resolved, white light, steady-state diffuse reflectance measurements were performed on normal and neoplastic tissue identified by a pathologist. Reflectance data were fit using a radiative transport model to obtain absorption (μ a ) and transport scattering coefficients (μ 0 s ), which define a characteristic light propagation distance, δ. Monte Carlo (MC) simulations of light propagation from cylindrical diffusing fibers were run using the optical properties extracted from each of the kidneys. Interpretable spectra were obtained from 14 kidneys. Optical properties of human renal cancers exhibit significant inter-lesion heterogeneity. For all diagnoses, however, there is a trend toward increased light penetration at longer wavelengths. For renal cell carcinomas (RCC), mean values of δ increase from 1.28 to 2.78 mm as the PDT treatment wavelength is increased from 630 to 780 nm. MC simulations of light propagation from interstitial optical fibers show that fluence distribution in tumors is significantly improved at 780 versus 630 nm. Our results support the feasibility of PDT in selected renal cancer patients, especially with photosensitizers activated at longer wavelengths.

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Section: Introductionmentioning

confidence: 99%

Optical property measurements establish the feasibility of photodynamic therapy as a minimally invasive intervention for tumors of the kidney

et al. 2012

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“…Patients with polycystic kidney disease were not included in the study. Ultrasonographic criteria for the diagnosis of a simple renal cyst included spherical or ovoid cyst, presence of a thin and smooth wall, absence of internal echoes and enhancement of the posterior wall, indicating ultrasound transmission through the water-filled cyst 15 . EGFR was estimated using modification of diet in renal disease study (MDRD) equation and eGFR< 60 ml/ min/1.73 m2 body surface area was considered as renal impairment.…”

Section: Methodsmentioning

confidence: 99%

Urinary Stones, Renal Cysts and Renal Impairment in Patients with Gout

Dhakad¹,

Singh²

2018

IJCMR

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Introduction: Urinary stones, renal cysts and renal failure are reported complications of gout. This study aimed to elucidate prevalence and relationship among them in gout patients. Material and Methods:In this prospective study, 107 patients with gout were included. Clinical assessment, BMI, comorbidities, dietary habits, urine microscopy, serum uric acid and renal functions were noted in all patients. Ultrasonography was used to detect urinary stones, renal cysts or any other abnormality in urinary system. Data was analysed using unpaired t test and Chi-square test. P value of <0.05 was considered statistically significant. Results:In gout patients urinary stones, renal cysts and impaired renal function were seen in 24.2% (26/107), 19.6% (21/107) and 28% (30/7) cases respectively. Serum uric acid level was significantly higher in those with impaired renal function. Occurrence of urinary stones was related to serum uric acid levels and duration of gout (p=0.038 and p < 0.0001). There was no association between renal stones and renal cysts (p=0.153). Presence of renal stones and duration of gout were associated with impaired renal function in gout patients (p=0.0011 and p=0.0006). Conclusions:Urinary stones and renal impairment are significant health problems in gout patients. Urinary stones and long standing disease are associated with renal impairment in gout.How to cite this article: Urmila Dhakad, Bhupendra Pal Singh. Urinary stones, renal cysts and renal impairment in patients with gout.

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“…MRI, especially with T2-weighted images, may be superior to CT in the correct characterization of benign lesions. 20 Choice of imaging techniques and their interpretation are discussed further in Chapter 5.…”

Section: Evaluation Of Asymptomatic Microscopic Hematuriamentioning

confidence: 99%