1998
DOI: 10.1016/s0022-3476(98)70231-8
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Radiologic progression in patients with juvenile chronic arthritis treated with methotrexate

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Cited by 60 publications
(34 citation statements)
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“…* The letters A through F correspond to the specific radiographs in Figure 4. Little information exists on the use of standardized scoring systems of joint radiographs in JIA (5)(6)(7)(8)(9)(10)(11). Recent studies have shown that the Poznanski method is a reliable and sensitive instrument for assessing radiographic progression in clinical and research settings and in therapeutic trials (6,7,9).…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…* The letters A through F correspond to the specific radiographs in Figure 4. Little information exists on the use of standardized scoring systems of joint radiographs in JIA (5)(6)(7)(8)(9)(10)(11). Recent studies have shown that the Poznanski method is a reliable and sensitive instrument for assessing radiographic progression in clinical and research settings and in therapeutic trials (6,7,9).…”
Section: Discussionmentioning
confidence: 99%
“…A number of scoring systems are available to quantify radiographic changes in adults with rheumatoid arthritis (3,4). However, little information exists on standardized measurement of radiographic damage in the investigation of disease outcome in children with juvenile idiopathic arthritis (JIA) (5)(6)(7)(8)(9)(10)(11). Furthermore, the assessment of radiographic progression has never been included in controlled trials of second-line agents in JIA.…”
Section: Introductionmentioning
confidence: 99%
“…Although this was not a treatment study, the vast majority of patients received second-line therapy. It is possible that aggressive therapy led to slowing down of radiographic damage in later years of the study, as has been demonstrated previously using the method of Poznanski [15,16].…”
Section: Destructive Changes By Plain Radiographymentioning
confidence: 72%
“…The greatest efficacy of methotrexate was seen in patients with extended oligoarthritis, while in a randomized study no significant effect was found in patients with systemic arthritis [Woo et al 2000;Ravelli et al 1999bRavelli et al , 1994Halle and Prieur, 1991]. Two small uncontrolled series have demonstrated that methotrexate may decrease the rate of progression of radiographic joint damage [Ravelli et al 1998;Harel et al 1993]. …”
Section: Disease-modifying Antirheumatic Drugsmentioning
confidence: 99%