Radiologic Pulmonary Findings, Clinical Manifestations and Serious Complications in Scrub Typhus: Experiences From A Teaching Hospital in Eastern Taiwan

Krishnamurthy

Journal of Infection and Public Health

et al. 2012

112

134

Section: Discussionmentioning

confidence: 99%

Scrub typhus in children at a tertiary hospital in southern India: Clinical profile and complications

Krishnamurthy

Journal of Infection and Public Health

et al. 2012

112

134

The American Society of Tropical Medicine and Hygiene

“…1 Presence of an eschar is a useful sign for diagnosing scrub typhus infection. Complications usually develop after the second week of illness, particularly in untreated cases, with systemic involvement 3 and disseminated vasculitis, 4 including septic shock, 5 acute respiratory distress syndrome (ARDS), 6,7 pneumonitis, 7 acute renal failure (ARF), 8,9 meningitis or meningoencephalitis, 10 myocarditis, 11 disseminated intravascular coagulation (DIC), 12 upper gastrointestinal bleeding, 13 and multiorgan dysfunctions (MODS). 1,4 Myocarditis is a rare complication, few reports showed abnormal electrocardiographic (ECG) findings in scrub typhus patients.…”

Section: Introductionmentioning

confidence: 99%

Scrub Typhus in Northeastern Thailand: Eschar Distribution, Abnormal Electrocardiographic Findings, and Predictors of Fatal Outcome

Thipmontree

Tantibhedhyangkul

Silpasakorn

et al. 2016

Abstract. Scrub typhus is endemic in Thailand. Of the 495 patients with acute undifferentiated fever studied in Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima, Thailand, from June 1, 2011, to December 31, 2012, 146 patients (29.5%) had confirmed scrub typhus. The majority of cases were male, farmers, with the mean (±standard deviation) age of 54.1 ± 15.2 years. A total of 59 patients (40.4%) had eschar lesion. The commonest sites for an eschar in male patients were the perineum, inguinal, and buttock area; whereas in females, it was the head and neck area. Abnormal electrocardiogram was found in 39 of 79 patients (49.4%) with sinus tachycardia being the most frequent finding (17, 21.5%). A total of 73 patients (50%) had at least one complication. Myocarditis was the cause of complete heart block in a scrub typhus patient, and he fully recovered after receiving intravenous chloramphenicol treatment. The case fatality rate was 6.2% (nine deaths).The independent predictors for fatal outcome were age over 65 years (odds ratio [OR] = 14.49, 95% confidence interval [CI] = 1.26-166.44, P = 0.03), acute kidney injury (OR = 12.75, 95% CI = 1.77-92.07, P = 0.01), and hyperbilirubinemia (OR = 24.82, 95% CI = 2.12-286.61, P = 0.01). Early diagnosis and prompt appropriate treatment can improve the patient's outcome.

“…It affects people of all ages, both the sexes and all ethnic groups. Eschar is usually present in the axilla, neck, groin, waist or inguinal area and its presence provides an important clue to the disease in endemic areas 1. The presence of eschar in the axilla led to suspicion of this disease in our case.…”

Section: Introductionmentioning

confidence: 66%

“…Approximately one million cases are reported annually 1. It is primarily seen in people whose job or behaviour brings them into contact with mite infected habitats such as forest clearings, rice fields, grassy lands or riverbanks 2.…”

Section: Introductionmentioning

confidence: 99%

Pancreatitis in scrub typhus: a rare complication

Dhakal

Bhandari

2014

BMJ Case Reports

Scrub typhus is a zoonosis transmitted by a trombiculid mite which introduces bacteria of Orientia tsutsugamushi by its bite. The acute febrile illness is characterised by eschar at the site of the bite with maculopapular rashes and local and/or generalised lymphadenopathy. The disease is endemic in the tsutsugamushi triangle. Sikkim, a small Himalayan north-eastern state, is also not unaffected where outbreaks of the disease have been reported. The clinical spectrum of the disease ranges from mild to fatal depending on the virulence of the bacterial strain, susceptibility of the host and promptness of the treatment. In severe cases, there can be multiple organ involvement. Pancreatitis is a serious and unusual complication of this disease, which was seen in our presentation. A 22-year-old man, diagnosed to have scrub typhus, developed pancreatitis in the second week of the illness and responded well to medical treatment.