Radiological and Cytological Correlation of Breast Lesions with Histopathological Findings in a Tertiary Care Hospital in Costal Karnataka

Richie, Anto J; Mellonie, P

doi:10.21276/ijcmr.2019.6.2.23

Cited by 7 publications

(4 citation statements)

References 6 publications

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“…The sensitivity of sonomammography was 23.8% and specificity was 100%. Diagnostic accuracy was found to be 81.4% which was comparable as stated in other studies by Patil et al and Riche et al 10,14 On FNAC of all the 275 breast lumps studied, 22 patients (8.0%) had inconclusive reporting, 192 (69.8%) had benign diagnosis and 61 (22.2%) had malignant diagnosis on FNAC in the study group. These 192 patients were followed up for final histopathology where 2 patients turned out to be having malignancy.…”

Section: Discussionsupporting

confidence: 88%

Study of clinical, imaging and pathological assessment of breast lumps: an observational study

2020

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Background: A palpable lump in a woman’s breast could be benign or malignant and it requires prompt evaluation to confirm or exclude cancer. This study aims to establish the correlation between clinical and radiological parameters for provisional diagnosis of breast lumps and the role of histopathology for final diagnosis of these breast lumps.Methods: Total 275 female patients with palpable breast lumps were included in the study, where a detailed history was recorded and clinical examination was done. All patients underwent ultrasonography of the breast along with fine needle aspiration cytology or histopathology, wherever indicated.Results: Benign breast lumps were found more commonly in 18-30 years of age group whereas malignant breast lumps were seen more commonly in the 41-60 years age group and the incidence increased with age. Fixity to skin was present in 5.1% and fixity to chest wall was present in 5.8% respectively, and all of these cases turned out to be malignant.Conclusions: Attributing factors for suspicion of malignant lumps are advanced age, fixity to surrounding structures, presence of ulceration and peau’d orange breast skin appearance. Although for confirmation of malignancy from a suspected breast lump requires either cytology or histopathology of the excised specimen.

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Section: Discussionsupporting

confidence: 88%

Study of clinical, imaging and pathological assessment of breast lumps: an observational study

2020

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“…The BIRAD reporting system of mammography was introduced in 1993, since then it has become important diagnostic tool in predicting the likelihood of breast carcinoma. 25 In present study sensitivity and specificity of mammography for detecting malignancy in breast lesion was 87.5% and 94.11% respectively which correlates well with Richie et al 25 had sensitivity of 90.6% and specificity of 97.8% and shanibi et al 26 sensitivity of 88.8%.…”

Section: Discussionsupporting

confidence: 84%

Correlation of FNAC with Histopathology of breast lesions

Risaldar¹,

Begum²,

Alvi³

2020

JDPO

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Breast cancer is a commonest maliganancy of women globally. A papable breast lump is common diagnostic dilemma to surgeons. Fine needle aspiration cytology (FNAC) is simple rapid, accurate diagnostic tool for evaluating palpable breast lumps. Mammography is other screening modality for a breast lump which is routinely used method with simple, low cost with high accuracy. Aim: To differentiate and categories the breast lesions, and to study the correlation of FNAC with histopathology of palpable breast lumps.Materials and Methods: one and half year retrospective study carried out from January 2019 to June 2020 in the department of pathology, KBNIMS, Gulbarga. FNAC and Histopathology slides were retrieved and reviewed. All the slides were observed and findings recorded. Mammography findings were retrieved and recorded.Result: The present study includes 125 cases out of which 101 cases (80.8%) were benign and 24 cases (19.2%) were malignant. Most common benign breast lesion was fibroadenoma (52.4%) and malignant lesion was infiltrating ductal carcinoma (75%). Frequencies of left breast lesions were high compare to right breast lesions. Out of 125 cases FNAC, 123 cases (98.4%) correlated with histopathology with sensitivity of 91.66%, specificity of 100%, positive predictive value (PPV) of 100%, negative predictive value (NPV) of 98% and accuracy of 98.4%.Out of 125 cases, mammography of 25 cases were retrieved with sensitivity of 87.5% and specificity of 94.11% with diagnostic accuracy of 92%. Conclusion: FNAC is a valuable diagnostic tool; provide rapid and reliable diagnosis in breast lesions.

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“…12,17 The upper outside quadrant of the breast had the highest prevalence of lesions (45.2%), according to Rocha P D et al 14 Since its introduction in 1993, the BIRAD mammography reporting system has grown to be a crucial diagnostic tool for determining the likelihood of breast cancer. 18 In our investigation, BI-RADS-3 was reported for 9 patients (8.33%), BI-RADS-4 for 70 patients (64.81%), and BI-RADS-5 for 29 patients (26.85%). Six of the nine cases with a probable benign outcome (BI-RADS-3) were listed on FNAC as benign.…”

Section: Discussionmentioning

confidence: 43%

Comparative Evaluation of FNAC and USG Breast with Core Needle Biopsy in the Diagnosis of Malignant Breast Lesions: A Prospective Observational Study

Bhagat¹,

Sheikh

Choudhary³

2023

Int J Res Rev

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Background: There is no doubt that breast cancer is the most frequently diagnosed life-threatening cancer in women and a significant cause of cancer death among women in both developing and developed nations. Using breast imaging-reporting and data system (BI-RADS) classification and breast core needle biopsy (CNB) results, we compared the diagnostic efficacy of FNAC and ultrasonography breast in separating malignant from benign breast masses. Methods: After getting the approval from the Institutional Ethical Committee, the present prospective cross-sectional study was conducted in the Department of Pathology, Government Medical College, Srinagar (tertiary care hospital), Kashmir, India over a period of 2 years (July 2019 to June 2021). Results: With a mean age of (45.4±13.4) years, the age incidence among the 108 individuals ranged from 22 to 85 years, with the most common age group for breast lumps to occur being (30-39) years. Both FNAC and USG breast were compared to CNB (gold standard), they both had sensitivity and specificity values of (94.57%, 100%) and (95%, 50%), respectively. Conclusion: When FNAC and USG breast were compared to CNB, the gold standard test, FNAC was found to be more reliable and accurate for the identification of malignant breast lesions. However, when these two tests were utilised in tandem, a better outcome and diagnosis could be achieved. Keywords: Ultrasonography, FNAC, Core needle biopsy, Breast malignancy

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Radiological and Cytological Correlation of Breast Lesions with Histopathological Findings in a Tertiary Care Hospital in Costal Karnataka

Cited by 7 publications

References 6 publications

Study of clinical, imaging and pathological assessment of breast lumps: an observational study

Study of clinical, imaging and pathological assessment of breast lumps: an observational study

Correlation of FNAC with Histopathology of breast lesions

Comparative Evaluation of FNAC and USG Breast with Core Needle Biopsy in the Diagnosis of Malignant Breast Lesions: A Prospective Observational Study

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