Radiological approach to cavitary lung lesions

Canan, Arzu; Batra, Kiran; Saboo, Sachin S.; Landay, Michael; Kandathil, Asha

doi:10.1136/postgradmedj-2020-138694

Cited by 9 publications

(7 citation statements)

References 65 publications

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“…Of the 23 malignant cases in our study, primary lung cancer was detected in 20 (squamous cell carcinoma in 13, adenocarcinoma in 5, malignant mesenchymal tumor in 1, and small cell lung carcinoma in 1), and metastasis in 3 cases (melanoma in 1 and colorectal in 2). Cavitation may also develop after chemotherapy in primary or metastatic solid lung tumors, 3 although none of the cases in the present study underwent chemotherapy.…”

Section: Discussionmentioning

confidence: 63%

“…Cavitary lung lesions are common pathologies encountered radiologically. Cavitation may occur due to primary and metastatic malignant causes, or due to a wide range of pathologic conditions, such as infections, autoimmune diseases, traumas, and congenital lung malformations 3. To ensure the appropriate treatment of the disease it is very important to differentiate between malignant and benign cavitary lesions.…”

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confidence: 99%

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The Efficiency of Diffusion-weighted Magnetic Resonance Imaging in the Differentiation of Malign and Benign Cavitary Lung Lesions

Durmaz¹,

Özgökçe²,

Aydın

et al. 2023

Journal of Thoracic Imaging

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Purpose: The present study investigates the diagnostic efficiency of apparent diffusion coefficient (ADC) values in differentiating between malignant and benign cavitary lesions on diffusion-weighted magnetic resonance imaging (DWI). Materials and Methods: This prospective study included 45 consecutive patients identified with a cavitary lung lesion with a wall thickness of ≥5 mm on thoracic computed tomography in our clinic between 2020 and 2022, and who underwent thoracic DWI within 1 week of their original computed tomography. ADC measurements were made on DWI by drawing a region of interest manually from the cavity wall, away from the lung parenchyma in the axial section where the lesion was best demonstrated. The patients were then classified into benign and malignant groups based on the pathology or clinico-radiologic follow-up. Results: The sample included 29 (64.4%) male and 16 (35.6%) female patients, with a mean age of 59.06±17.3 years. Included in the study were 1 patient with 3 and 3 patients with 2 cavitary lesions each, with a total for the sample of 50 cavitary lesions. There were 23 (46%) malignant and 27 (54%) benign cavitary lung lesions. The mean ADC value (×10−3 mm2/s) of the malignant and benign cavitary lesions was 0.977±0.522 (0.511 to 2.872) and 1.383±0.370 (0.930 to 2.213), respectively. The findings were statistically significant using an independent samples t test (P=0.002). The mean wall thickness of the malignant and benign lesions was 12.47±5.51 mm (5 to 25 mm) and 10.11±4.65 mm (5 to 22 mm), respectively. Although malignant cavities had a higher mean wall thickness than benign cavities, the difference was statistically insignificant (P=0.104). Conclusion: A significant difference was identified between the ADC values measured in DWI of the malignant and benign cavitary lung lesions. DWI, a noninvasive and rapid imaging method, can provide useful information for the differential diagnosis of cavitary lesions and can minimize unnecessary biopsies.

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Section: Discussionmentioning

confidence: 63%

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confidence: 99%

The Efficiency of Diffusion-weighted Magnetic Resonance Imaging in the Differentiation of Malign and Benign Cavitary Lung Lesions

Durmaz¹,

Özgökçe²,

Aydın

et al. 2023

Journal of Thoracic Imaging

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“…We propose utilizing a clinical-radiological algorithm approach for the differential diagnosis of cavitary lung lesions. This entails evaluating their imaging characteristics via CT and PET-CT, and then combining these results with the patient's clinical symptoms and case features for diagnosis 2,8 . In the case we are discussing, the patient also had metastatic lesions in the liver and lymph nodes, a pattern that is consistent with the typical progression of gallbladder cancer metastasis 5,9 .…”

Section: Discussionmentioning

confidence: 99%

gallbladder carcinoma with Pulmonary cavitary lesions

Wang

Kang

Zhang

et al. 2023

Preprint

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“…An irregular, air-filled region inside the lung with thick walls is called a lung cavity, or pulmonary cavity. Lung cavities may result from pulmonary emboli, infections, cancer, autoimmune diseases, trauma, or congenital abnormalities [1][2].Lung cancer is the most frequent cause of a single lung cavity [3].Lung cavities are frequently caused by bacterial, mycobacterial, and fungal illnesses. [5] Probably the most common infectious cause of lung cavities worldwide is tuberculosis.…”

Section: Introductionmentioning

confidence: 99%

“…Diagnosis of a lung cavity is made with a chest X-ray or CT scan of the chest [2], which helps to exclude mimics like lung cysts, emphysema, bullae, and cystic bronchiectasis. [5] Once an imaging diagnosis has been made, a person's symptoms can be used to further narrow the differential diagnosis.…”

Section: Introductionmentioning

confidence: 99%

Study of cavernous lung lesions with malignant features

Khashifa,

Alloush,

khattab

2024

Preprint

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Introduction: Many different diseases present as cavitary pulmonary nodules. The spectrum of diseases ranges from acute to chronic infections, chronic systemic diseases, and malignancies. To decide on the most likely or correct diagnosis may be challenging. Knowledge of common and uncommon radiological findings in correlation with relevant clinical history and findings is necessary to make the right diagnosis and recommend the correct follow-up or step forward. The aim of this pictorial review is to present a brief overview of CT findings of common cavitary lung diseases seen in adult patients. Methods and materials: Radiologically diagnosed lesions were reviewed and studied as pulmonary lesions in the pulmonary parenchyma. 232 malignant cavernous lesions were detected by referring to patient files, patient records and radiological archives at Damascus Hospital from 2020 to 2024. Results: The percentage of males was 55% and the percentage of females was 45%, ages over 40 years were 58% and under 40 years were 42%. On the chest image, a thickness of the cavern wall was found to be more than 3 cm (35%), and a thickness of more than 5 mm (65%), irregular edges on one side of the cavern 25%, and irregular edges on both sides 75%, calcification was found in 3%, and suspicion of its cancer was desquamative (35%). Conclusion: Do not neglect any pulmonary cavern, because it may be a pulmonary neoplasm, and the best solution to diagnose pulmonary caverns is to perform positron emission tomography (PET-CT).

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Radiological approach to cavitary lung lesions

Cited by 9 publications

References 65 publications

The Efficiency of Diffusion-weighted Magnetic Resonance Imaging in the Differentiation of Malign and Benign Cavitary Lung Lesions

The Efficiency of Diffusion-weighted Magnetic Resonance Imaging in the Differentiation of Malign and Benign Cavitary Lung Lesions

gallbladder carcinoma with Pulmonary cavitary lesions

Study of cavernous lung lesions with malignant features

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