Radiological assessment of pulmonary oedema: a new principle. Oleic acid lung injury

Wegenius, G.; Wickerts, C.‐J.; Hedenstierna, Göran

doi:10.1007/bf00231201

Cited by 7 publications

(1 citation statement)

References 20 publications

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“…However, this technique is In addition to morphological information, computed tomography (CT) can supply data on the absolute tissue density [7], In the case of the lung, which exhibits a wide density range from air to blood, the CT scan is useful for evaluating the density associated with normal and patho logical states. This technique was first used to study differ ent forms of pulmonary edema in animal models [8,9], It was then applied in humans to investigate lung edema in patients with acute respiratory distress syndrome and congestive heart failure [10,11],…”

Section: Introductionmentioning

confidence: 99%

Computed Tomographic Measurement of Lung Density Changes in Lung Water with Hemodialysis

Metry¹,

Wegenius²,

Hedenström³

et al. 1997

Nephron

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In 10 hemodialysis patients, with an ultrafiltration volume ranging from 1 to 4.5 liters per session, the lung density was measured by computed tomography (CT) and the lung volumes by total body plethysmography. From the CT numbers (difference in X-ray attenuation between lung and water, measured in Hounsfield units, HU), and by using a special computer program, quantitative estimates of the densities of normally inflated (pixels between -1,000 and -500 HU), poorly inflated (pixels between -500 and -100 HU) and noninflated lung tissue (pixels between -100 and +100 HU) were obtained. The sizes of the normally and poorly inflated areas were also measured. The results showed that, after dialysis, the normally inflated area was decreased in density and increased in size, and conversely, the size of the poorly inflated area was diminished but without change in density. This finding implied introduction of more gas into the lung. The above observation was reflected by the results of pulmonary function measurements, in that the total lung capacity and functional residual capacity were significantly increased after dialysis. In conclusion, changes in lung fluid (both intra- and extravascular) with hemodialysis can be measured quantitatively by the changes in lung density as estimated by the CT densitometry technique.

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Section: Introductionmentioning

confidence: 99%

Computed Tomographic Measurement of Lung Density Changes in Lung Water with Hemodialysis

Metry¹,

Wegenius²,

Hedenström³

et al. 1997

Nephron

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Lung Damage by Artificial Ventilation Proof by Radiological Techniques

Wegenius¹

1998

Anaesthesia, Pain, Intensive Care and Emergency Medicine - A.P.I.C.E.

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Automatic detection of ground glass opacities on lung HRCT using multiple neural networks

et al. 1997

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The purpose of this study was to implement neural networks and expert rules for the automatic detection of ground glass opacities (GG) on high-resolution computed tomography (HRCT). Different approaches using self-organizing neural nets as well as classifications of lung HRCT with and without the use of explicit textural parameters have been applied in preliminary studies. In the present study a hybrid network of three single nets and an expert rule was applied for the detection of GG on 120 HRCT scans from 20 patients suffering from different lung diseases. Single nets alone were not capable to reliably detect or exclude GG since the false-positive rate was greater than 100 % with regard to the area truly involved, more than 50 pixels throughout, and the true-positive rate was greater than 95 %. The hybrid network correctly classified 91 of 120 scans. Mild GG was false positive in 15 cases with less than 50 pixels, which was judged not clinically relevant. The pitfalls were: partial volume effects of bronchovascular bundles and the chest wall. Motion artefacts and diaphragm were responsible for 11 misclassifications. Hybrid networks represent a promising tool for an automatic pathology-detecting system. They are ready to use as a diagnostic assistant for detection, quantification and follow-up of ground glass opacities, and further applications are underway.

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Radiological assessment of pulmonary oedema: a new principle. Oleic acid lung injury

Cited by 7 publications

References 20 publications

Computed Tomographic Measurement of Lung Density Changes in Lung Water with Hemodialysis

Computed Tomographic Measurement of Lung Density Changes in Lung Water with Hemodialysis

Lung Damage by Artificial Ventilation Proof by Radiological Techniques

Automatic detection of ground glass opacities on lung HRCT using multiple neural networks

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