Radiological features of head and neck mammary analogue secretory carcinoma: 11 new cases with a systematic review of 29 cases reported in 28 publications

Kurokawa, Ryo; Kurokawa, Mariko; Baba, Akira; Ota, Yoshiaki; Moritani, Toshio; Srinivasan, Ashok

doi:10.1007/s00234-021-02796-7

Cited by 8 publications

(5 citation statements)

References 45 publications

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“…MASC was first described in 2010 as a rare salivary carcinoma mimicking acinar cell carcinoma and was released to the World Health Organization classification of head and neck tumors in 2017[ 71 , 72 ]. MASC has morphological and genetic similarities with secretory carcinoma of the breast.…”

Section: Salivary Gland Mtsmentioning

confidence: 99%

“…MASC has morphological and genetic similarities with secretory carcinoma of the breast. The majority of MASCs (approximately 70%-80%) are located in the parotid gland, while a smaller number are located in other minor salivary gland areas or major salivary gland glands[ 72 , 73 ]. MASCs are often tumors of “papillary and cystic” or “non-papillary and cystic” morphology.…”

Section: Salivary Gland Mtsmentioning

confidence: 99%

“…The cystic and solid components of these tumors have high signal on T1WIs on MRI, more often in the cystic component. On contrast-enhanced MRI series, solid components may show different forms of enhancement (homogeneous, heterogeneous, or scarce)[ 72 ]. DWI has been applied in a limited number of cases in MASCs, and ADC values in the solid components of the tumor vary between (0.5-1.7) × 10 -3 mm 2 /s[ 70 , 72 ].…”

Section: Salivary Gland Mtsmentioning

confidence: 99%

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Advanced magnetic resonance imaging findings in salivary gland tumors

Gökçe

Beyhan

2022

WJR

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Salivary gland tumors (SGTs) make up a small portion (approximately 5%) of all head and neck tumors. Most of them are located in the parotid glands, while they are less frequently located in the submandibular glands, minor salivary glands or sublingual gland. The incidence of malignant or benign tumors (BTs) in the salivary glands varies according to the salivary gland from which they originate. While most of those detected in the parotid gland tend to be benign, the incidence of malignancy increases in other glands. The use of magnetic resonance imaging (MRI) in the diagnosis of SGTs is increasing every day. While conventional sequences provide sufficient data on the presence, localization, extent and number of the tumor, they are insufficient for tumor specification. With the widespread use of advanced techniques such as diffusion-weighted imaging, semi-quantitative and quantitative perfusion MRI, studies and data have been published on the differentiation of malignant or BTs and the specificity of their subtypes. With diffusion MRI, differentiation can be made by utilizing the cellularity and microstructural properties of tumors. For example, SGTs such as high cellular Warthin’s tumor (WT) or lymphoma on diffusion MRI have been reported to have significantly lower apparent diffusion values than other tumors. Contrast agent uptake and wash-out levels of tumors can be detected with semi-quantitative perfusion MRI. For example, it is reported that almost all of the pleomorphic adenomas show an increasing enhancement time intensity curve and do not wash-out. On quantitative perfusion MRI studies using perfusion parameters such as Ktrans, Kep, and Ve, it is reported that WTs can show higher Kep and lower Ve values than other tumors. In this study, the contribution of advanced MRI to the diagnosis and differential diagnosis of SGTs will be reviewed.

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Section: Salivary Gland Mtsmentioning

confidence: 99%

Section: Salivary Gland Mtsmentioning

confidence: 99%

Section: Salivary Gland Mtsmentioning

confidence: 99%

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Advanced magnetic resonance imaging findings in salivary gland tumors

Gökçe

Beyhan

2022

WJR

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“…Out of a total of 226 studies published between 2010 and 2023, identified at initial search and screened for retrieval, 112 1–3,6–114 articles were included in the study, with a total of 674 patients described in these articles. The identification and screening process is described in Figure 1.…”

Section: Resultsmentioning

confidence: 99%

Salivary Gland Secretory Carcinoma; Review of 13 Years World‐Wide Experience and Meta‐Analysis

Yosefof,

Boldes,

Dan

et al. 2023

The Laryngoscope

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ObjectivesSecretory Carcinoma is a malignant salivary gland tumor, initially described in 2010. This rare tumor is associated with the translocation t(12;15) (p13;q25), resulting in the fusion gene ETV6‐NTRK3. Since this tumor is quite rare, most publications describe only small cohorts of patients. We aimed to investigate the clinical, pathological, and prognostic features of this newly defined malignant entity.Data SourcesPubmed, Google Scholar, and Web of Science databases.Review MethodsAll published articles between 2010 and 2023 were reviewed. Search terms included the terms “Mammary Analogue Secretory Carcinoma” and “Secretory Carcinoma”. All articles published in English reporting on Secretory Carcinoma of salivary glands were retrieved.ResultsOne‐hundred and 12 retrospective articles reporting a total of 674 patients were included, with 52% males and a mean age of 44.9 ± 18.9. The event rate for patients with advanced‐stage disease (Stage 3/4) at presentation was 24.1% (95% CI 17.6%–31.9%, I2 = 9.2%), 14.6% for regional metastases (95% CI 10.5%–20%, I2 = 12%), and the event rate of distant metastasis was 8.4% (95% CI 5.5%–12.7%, I2 = 4.2%). Adjuvant radiotherapy was administered for 30.3% of patients (95% CI 24.1%–37.2%, I2 = 21.5%). The recurrence rate was 19% (95% CI 15.1%–23.8%, I2 = 5%). Survival outcomes showed a 17.2% death of disease rate for Secretory Carcinoma patients (95% CI 13.5%–21.8%, I2 = 7.3%).ConclusionsSecretory Carcinoma is a rare and relatively newly defined entity arising in the parotid gland most commonly. Characterized as a low‐grade tumor, the majority of patients are diagnosed at an early stage, without regional or distant disease, and the prognosis is relatively good.Level of EvidenceN/A Laryngoscope, 2023

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“…We reviewed case-based studies using the widely accepted tool to evaluate the methodological quality of case reports and case series proposed by Murad et al, [17][18][19][20][21][22][23][24][25] which is based on four domains (selection, ascertainment, causality, and reporting) and eight signaling questions.…”

Section: Quality Assessmentmentioning

confidence: 99%

MRI features of sinonasal tract angiofibroma/juvenile nasopharyngeal angiofibroma: Case series and systematic review

Baba

Kurokawa

et al. 2023

Journal of Neuroimaging

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Background and PurposeTo comprehensively summarize the radiological characteristics of sinonasal tract angiofibroma (STA) (commonly known as juvenile nasopharyngeal angiofibroma).MethodsForty‐four lesions from 41 cases provided by 33 study articles identified through a systematic review and 13 lesions from 13 cases from our institution associated with patients with STA who underwent MRI were included in the review study, carried out by two board‐certified experienced radiologists.ResultsThe study participants were all male patients with a mean age of 15.6 years at the time of diagnosis. All of them presented with nasal cavity lesions (100%), predominantly in the nasopharynx (98.2%). The sphenopalatine foramen/pterygopalatine fossa was involved in 76.0%, and compressive shift of the posterolateral wall of the maxillary sinus was present in more than half (57.9%). T2‐weighted imaging signal intensity was heterogeneous with mixed high and iso intensities as compared to skeletal muscle (100%). T1‐weighted imaging showed partial high signal intensity in 61.1% of the cases. Flow void and intense enhancement were present in almost all cases. Cystic/nonenhancement changes on contrast‐enhanced MRI were relatively common (40.8%). The mean apparent diffusion coefficient value (2.07 × 10−3 mm2/second) and some quantitative dynamic contrast‐enhanced MRI parameters were high. There was a significant difference in the frequency of residual/recurrent lesions based on the presence of MRI findings of skull base invasion (p = .017) and intracranial extension (p = .003).ConclusionsWe summarized the MRI findings of STA that can facilitate timely diagnosis and appropriate management.

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Radiological features of head and neck mammary analogue secretory carcinoma: 11 new cases with a systematic review of 29 cases reported in 28 publications

Cited by 8 publications

References 45 publications

Advanced magnetic resonance imaging findings in salivary gland tumors

Advanced magnetic resonance imaging findings in salivary gland tumors

Salivary Gland Secretory Carcinoma; Review of 13 Years World‐Wide Experience and Meta‐Analysis

MRI features of sinonasal tract angiofibroma/juvenile nasopharyngeal angiofibroma: Case series and systematic review

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