Radiological outcomes for endovascular treatment of posterior communicating artery aneurysms: a retrospective multicenter study of the occlusion rate

Abstract

Although several innovations in techniques and implantable devices were reported over the last decades, a consensus on the best endovascular treatment for intracranial aneurysms originating from the posterior communicating artery is still missing. This work investigates radiological outcomes of different endovascular techniques for posterior communicating artery aneurysms treatment in a retrospective multi-centric cohort. We included patients endovascularly treated for posterior communicating artery aneurysms from 2015 through 2020 in six tertiary referral hospitals. We evaluated the relationship between patients and aneurysms characteristics, baseline neurological status, radiological outcomes, and the different endovascular techniques. Overall, 250 patients were included in this study. Simple coiling was the most frequent treatment in 171 patients (68%), followed by flow-diverter stenting in 32 cases (13%). Complete occlusion was reported in 163 patients (65%), near-complete occlusion in 43 (17%), and incomplete occlusion in 44 (18%). Radiological follow-up was available for 247 (98%) patients. The occlusion rate was stable in 149 (60%), improved in 49 (19%), and worsened in 51 (21%). No significant difference in exclusion rate was seen between ruptured and unruptured aneurysms at the last follow-up (p = 0.4). Posterior communicating artery thrombosis was reported in 25 patients (9%), transient ischemic attack in 6 (2%), and in 38 patients (15%), subsequent procedures were needed due to incom-plete occlusion or reperfusion. Endovascular strategies for posterior communicating artery aneurysms represent effective and relatively safe treatments. Simple coiling provides a higher immediate occlusion rate, although recanalization has been frequently reported, conversely, flow-diversion devices provide good long-term radiological outcomes.

Timing and outcome of bystanders treatment in patients with subarachnoid hemorrhage associated with multiple aneurysms

“…Bystanders treatment was also effective and the occurrence of a previous SAH did not appear a limitation neither from a surgical nor from an endovascular point of view. Only three minimal remnants were observed as a result of a minimal neck sparing to guarantee the collateral perfusion in two cases of PICA and PCom aneurysms with junctional morphology [ 32 ], and another due to a still incomplete obliteration in a flow-diverted ophthalmic ICA aneurysm.…”

Geometry and Symmetry of Willis’ Circle and Middle Cerebral Artery Aneurysms Development

“…ACom and PCom artery aneurysms are the most common IAs, accounting for 23-40% and 15-20% of IAs, respectively, and are more likely to rupture than other types of IAs because of their anatomic and hemodynamic characteristics [41][42][43]. The asymmetry of the proximal segment of the ACA and fetal pattern of the PCom artery are more often found in patients with ruptured aneurysms in these locations [44][45][46]. The association between circle of Willis anomalies and aneurysm rupture in previous reports has been primarily descriptive [5,[47][48][49] or consisted of much fewer cases.…”