Radiological outcomes of whole lung lavage for artificial stone‐associated silicosis

Chambers, Daniel C.; Apte, Simon H.; Deller, David; Masel, P.; Jones, C. T.; Newbigin, Katrina; Matula, Michael; Rapchuk, Ivan L.

doi:10.1111/resp.14018

Cited by 14 publications

(12 citation statements)

References 9 publications

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“…There is no known cure for silicosis, although several classes of medication that target inflammatory and fibrotic pathways have been identified as possibilities for clinical trials 3 . Whole lung lavage showed radiological improvement in a case series of six workers, 11 and lung transplantation may be available for eligible workers with severe disease, with equivalent 1‐year 7 and longer‐term survival 12 compared to other lung transplant recipients. The progression of silicosis and death has been reported even after the cessation of RCS exposure in stonemasons and denim workers with RCS exposure 13,14 .…”

Section: Introductionmentioning

confidence: 99%

Predictors of psychological stress in silica‐exposed workers in the artificial stone benchtop industry

et al. 2022

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Background and objective Artificial stone benchtops are a popular kitchen product, but dust from their preparation and installation contains respirable crystalline silica, which causes silicosis. Silicosis is a preventable, permanent lung disease. The aim of this study was to assess mental health in workers from the artificial stone benchtop industry at risk of silicosis. Methods Workers from the artificial stone benchtop industry undergoing assessment for silica‐associated disease were included. Information on demographics; occupational, medical and smoking history; modified Medical Research Council dyspnoea scale; Perceived Stress Scale (PSS‐10) questionnaire; spirometry; and chest x‐ray was collected. Univariate and multivariate regression analyses were conducted. Results Of the 547 participants, the majority were men, aged under 45 years, in the industry for less than 10 years. With each increase of dyspnoea score, PSS‐10 scores increased. Higher PSS‐10 scores were also observed in those no longer in the industry, with a history of anxiety or depression, attending assessment early in the programme and a medium exposure duration. Participants who used an interpreter reported lower stress. No difference was observed across job title, age, sex, smoking, spirometry or chest x‐ray categories after multivariate analysis. Conclusion This study identified workers with dyspnoea as likely to report higher stress. Other factors, such as leaving the industry, early attendance and a history of anxiety or depression, are also helpful in identifying workers at risk of poorer mental health outcomes.

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Section: Introductionmentioning

confidence: 99%

Predictors of psychological stress in silica‐exposed workers in the artificial stone benchtop industry

et al. 2022

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“…Lung transplantation is considered to be the only definitive management option. Favorable short-term clinical [10] and radiological [11] response to therapeutic whole lung lavage (WLL), a staple of PAP management, has been reported in silicoproteinosis, but more robust data to support its use are lacking. Evidence of efficacy of corticosteroids in silicoproteinosis is likewise anecdotal [12].…”

Section: Clinical Discussionmentioning

confidence: 99%

A 44-year-old stone worker with progressive dyspnea: lessons from a new twist on an old foe

Manglani

Akbar

Beasley

et al. 2022

Monaldi Arch Chest Dis

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Silicosis is typically an indolent lung disease caused by long-standing occupational exposure to respirable crystalline silica, classically in professions such as sandblasting and mining. An increasingly popular industry that has earned particular interest because of its association with silicosis is customization and installation of artificial stone countertops for domestic applications. In addition to causing a spike in cases of chronic and accelerated silicosis, both quite familiar to respiratory clinicians, outbreaks of artificial stone silicosis have brought to the fore a historically rare entity known as acute silicosis, or silicoproteinosis, a more rapid presentation of the disease. Failure to suspect this uncommon condition can lead to diagnostic confusion and therefore ineffective treatment as was true initially of the patient we describe herein. The case description is followed by a clinical, radiological, and pathological overview of acute artificial stone silicosis (or silicoproteinosis), which is an emerging pneumoconiosis with sparse coverage in the literature to date. This case also adds to the few existing reports on the use of therapeutic whole lung lavage for silicoproteinosis.

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“…Using a standardized high resolution computed tomography of the chest scoring system, WLL led to nearly complete resolution of the “semi-solid centrilobular nodules in five of the six” workers without extensive fibrosis. Neither the amount of dust removed nor the follow-up effect on symptoms, imaging, or lung function was reported 41 …”

Section: Discussionmentioning

confidence: 99%

“…Neither the amount of dust removed nor the follow-up effect on symptoms, imaging, or lung function was reported. 41 Finally, the reports used in this analysis leave numerous unanswered questions. Specifically, we do not have a description of the reliability and reproducibility of the lung function tests.…”

Section: Discussionmentioning

confidence: 99%

The Effectiveness of Whole Lung Lavage in Pneumoconiosis

Zeng

Jiang

Banks

2022

Journal of Occupational &Amp; Environmental Medicine

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Radiological outcomes of whole lung lavage for artificial stone‐associated silicosis

Cited by 14 publications

References 9 publications

Predictors of psychological stress in silica‐exposed workers in the artificial stone benchtop industry

Predictors of psychological stress in silica‐exposed workers in the artificial stone benchtop industry

A 44-year-old stone worker with progressive dyspnea: lessons from a new twist on an old foe

The Effectiveness of Whole Lung Lavage in Pneumoconiosis

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