Radiological significance of mediastinal lymphadenopathy in eosinophilic granulomatosis with polyangiitis

Sasaki, Hisashi; Miyata, Jun; Suematsu, Ryohei; Kimizuka, Yoshifumi; Fujikura, Yuji; Kichikawa, Yoshiko; Sugiura, Hiroaki; Itoh, Kenji; Kawana, Akihiko

doi:10.1016/j.alit.2022.05.011

Cited by 3 publications

(2 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Interestingly, recent research suggests that patients with eosinophilia and asthma exhibiting low serum C-reactive protein levels at diagnosis might lean towards idiopathic hypereosinophilic syndrome rather than ANCA-negative EGPA[ 13 ]. Moreover, mediastinal lymphadenopathy has emerged as a hallmark of systemic inflammation in EGPA[ 3 ]. The presence of both these indicators, C-reactive protein levels and mediastinal lymphadenopathy, in our patient, further solidified the diagnosis of ANCA-negative EGPA.…”

Section: Discussionmentioning

confidence: 99%

“…Eosinophilic granulomatosis with polyangiitis (EGPA) is an anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis characterized by asthma, infiltrative necrotizing vasculitis, extravascular granulomas, eosinophilia, and multi-organ infiltration[ 1 ]. Despite the association between EGPA and ANCA, only 30%-40% of patients with EGPA produce ANCAs[ 2 , 3 ]. Therefore, patients can be divided into two subtypes: ANCA-positive patients who typically experience vasculitis-related symptoms (purpura, neuropathy, pulmonary-renal syndrome), and ANCA-negative patients who are more likely to experience eosinophil-driven symptoms (pulmonary infiltrates, cardiomyopathy)[ 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Eosinophilic granulomatosis with polyangiitis, asthma as the first symptom, and subsequent Loeffler endocarditis: A case report

He,

Liu,

Zhang

et al. 2023

World J Clin Cases

View full text Add to dashboard Cite

In recent years, metabolomics research has become a hot spot in the screening and treatment of cancer. It is a popular technique for the quantitative characterization of small molecular compounds in biological cells, tissues, organs or organisms. Further study of the tumor revealed that amino acid changes may occur early in the tumor. The rapid growth and metabolism required for survival result in tumors exhibiting an increased demand for amino acids. An abundant supply of amino acids is important for cancer to maintain its proliferative driving force. Changes in amino acid metabolism can be used to screen malignant tumors and improve therapeutic outcomes. Therefore, it is particularly important to study the characteristics of amino acid metabolism in colorectal cancer. This article reviews several specific amino acid metabolism characteristics in colorectal cancer.

show abstract

Section: Discussionmentioning

confidence: 99%