“…1 Among the many types of 3D printing techniques, fused filament fabrication (FFF) or fused deposition modeling (FDM) is one of the widely used techniques in pharmaceutical applications to generate 3D dosage forms because of its cost-effectiveness, affordability, lack of a requirement for solvents, ease of use, and precisely controlled size and complex geometries of printlet with remarkable reproducibility. [2][3][4][5] In the FFF process, a thermoplastic polymer filament is melt, extruded through a high temperature nozzle and then hardened layer by layer onto a platform until printing was completed. 6 FFF requires filament with good mechanical properties and thermoplastic characteristics.…”