Radiology–pathology conference: malignant solitary fibrous tumor of the seminal vesicle

Khandelwal, Ashish; Virmani, Vivek; Amin, Md. Shahrier; George, Uttam; Khandelwal, Kanika; Gorsi, Ujjwal

doi:10.1016/j.clinimag.2012.04.027

Cited by 11 publications

(12 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To our knowledge, reports of SFTs from numerous extrapleural locations are most common in the literature and these include localization to the retroperitoneal, intrameningeal, or pelvic space; the thyroid or mammary gland; the cervical spine, the orbital space, and in the extremities. 27 , 28 Of identified 20 patients with SFTs, 60% were extrapleural.…”

Section: Discussionmentioning

confidence: 99%

Variable Solitary Fibrous Tumor Locations

et al. 2016

View full text Add to dashboard Cite

The aim of the study is to describe the radiological imaging features of different solitary fibrous tumors (SFTs) locations and present histopathological correlations.From 2007 to 2013, 20 cases of histologically confirmed that SFTs were retrospectively analyzed with computed tomography (CT; 9/20), magnetic resonance imaging (MRI; 5/20), or both CT and MRI (6/20).All 20 SFTs were well defined, lobular, soft-tissue masses, and 60% were located outside of the pleura. One pleural case invaded to the 10th thoracic vertebra and had lung metastases. Images revealed 11 heterogeneous lesions that exceeded 3.0 ± 0.203 cm along the greatest axis with patchy necrotic foci, and 9 homogeneous lesions <3.0 ± 0.203. Microscopically, all SFTs were proliferative spindle cells with varying degrees of fibrosis and interspersed vessel branching. Cells were strongly immunopositive for CD34.Here we review variable imaging findings of SFTs, which can be within the pleura as well as within other serosal tissues such as the meninges and postperitoneum. SFTs > 3.0 ± 0.203 cm along the greatest axis appeared to be mixed patterns, whereas SFTs < 3.0 ± 0.203 cm had isodense appearances. SFTs cells were CD34 immunopositive and surgery was a first-line treatment choice.

show abstract

Section: Discussionmentioning

confidence: 99%

Variable Solitary Fibrous Tumor Locations

et al. 2016

View full text Add to dashboard Cite

show abstract

“…After gadolinium administration, all cases showed marked heterogeneous enhancement with hypointense areas. Khandelwal et al 14 reported that the intratumoural hypointense areas on T 1 weighted images correlated with myxoid or cystic degeneration. Kim et al 15 reported that isointense to hypointense signal intensity on T 2 weighted images reflected fibrous tissue with high collagen content, and hyperintense signal intensities were related to internal haemorrhage, cystic degeneration or relatively fresh fibrosis.…”

Section: Discussionmentioning

confidence: 99%

MRI findings of solitary fibrous tumours in the head and neck region

Liu¹,

Tao²,

Shi³

et al. 2014

Dentomaxillofacial Radiology

View full text Add to dashboard Cite

Objectives: To analyse the MRI findings of solitary fibrous tumours in the head and neck region. Methods: We retrospectively reviewed MR images in eight patients with solitary fibrous tumours proven on histological examination. All the patients underwent conventional MRI, and four patients also underwent dynamic contrast-enhanced MRI and diffusion-weighted imaging in five cases. Image characteristics were analysed. Results: All lesions were found as solitary well-defined masses ranging in size from 1.9 to 6.8 cm (mean, 4.1 cm). They were mostly homogeneous and isointense to the muscle on T 1 weighted images and heterogeneous and mildly hyperintense on T 2 weighted images. After gadolinium administration, areas that were mildly hyperintense on T 2 weighted images were strongly enhanced. They were mildly hyperintense on diffusion-weighted imaging. The average tumour-apparent diffusion coefficient values were 0.001 157 ± 0.000 304 9 mm s 22 compared with the muscle 0.000 760 ± 0.000 265 0 mm s 22 , and there was a statistical difference of p 5 0.002. The time-intensity curves exhibited a rapidly enhancing and a slow washout pattern on dynamic contrast-enhanced MRI. Conclusions: Solitary fibrous tumours should be considered in cases of heterogeneous hypervascular tumours in the head and neck region. Areas of mild hyperintense intensity on T 2 weighted images that are strongly enhanced after gadolinium injection are suggestive of this diagnosis. Non-restricted diffusion and rapidly enhancing and slow washout pattern time-intensity curves may be additional valuable features.

show abstract

“…SFT originating from the seminal vesicle affects the age range of 46 to 65 years (mean, 52 years) according to the previous findings. [7] SFT that is found in the seminal vesicle generally causes no discomfort and is usually occasionally found in physical examinations. SFTs are reported to be benign tumors in most cases, but approximately 6% of them have shown to be recurrent and/or lead to metastatic diseases.…”

Section: Discussionmentioning

confidence: 99%

“…[10] Morphology shows the tumor cells are monotonous and ovoid-to-spindle shaped. [7] Alternating hypocellular and hypercellular areas, rich blood vessels, hyaline degeneration of the vesicular wall, and collagen bundles in between the cells are commonly observed. Immunohistochemistry reveals that the tumor cells are positive for CD34, [11] CD99, vimentin, and Bcl-2, [12,13] which are necessary for establishing the diagnosis of SFT.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Solitary fibrous tumor of the seminal vesicle

Zhao

Shan²,

Zou³

et al. 2019

Medicine

View full text Add to dashboard Cite

Rationale:Solitary fibrous tumor (SFT) is an unusual neoplasm, especially when it originates from the seminal vesicle. Herein, we describe a case of SFT that arises from the seminal vesicle.Patient concerns:A 66-year-old man presented to our hospital complaining of a huge irregular tumor in his pelvis during a health checkup. He was worried that the tumor could be a malignant tumor and hence wanted to undergo further examination and therapy.Diagnosis:An inhomogeneous, mixed soft tissue tumor in the pelvis was found during computed tomography (CT) and magnetic resonance imaging. The tumor showed heterogeneous and delayed enhancement during contrast-enhanced CT. The tumor was diagnosed as a cystadenoma originated from the seminal vesicle due to its imaging features. But the pathological diagnosis was SFT that originated from the seminal vesicle.Interventions:Laparoscopic seminal vesicle tumor resection was performed.Outcomes:There was no evidence of recurrence at the 6-month follow-up.Lessons:SFT in the seminal vesicle is extremely rare. It is very difficult to distinguish SFT in the seminal vesicle from the primary tumors as both have similar imaging features. We describe the tumor with SFT being considered as a differential diagnosis when the tumor is found in the seminal vesicle.

show abstract

Radiology–pathology conference: malignant solitary fibrous tumor of the seminal vesicle

Cited by 11 publications

References 9 publications

Variable Solitary Fibrous Tumor Locations

Variable Solitary Fibrous Tumor Locations

MRI findings of solitary fibrous tumours in the head and neck region

Solitary fibrous tumor of the seminal vesicle

Contact Info

Product

Resources

About