Radiology's Role in the Battle against Pediatric Cancers

Pediatric abdominal tumors have many different etiologies; most of them are generally benign. Malignant tumors are rare, but early diagnosis and work-up are essential to ensure patient's cure. Diffusion-Weighted Images (DWI) helps providing functional information at a microscopic level of the movement of water. DWI has being increasingly utilized in body oncology imaging for both tumor detection and therapy evaluation, and is particularly promising in children due to the large proportion of small round cell tumors which demonstrate restricted water diffusion. This technique has been applied specially as a noninvasive radiation-free cancer staging and follow up. This article reviews the diffusion magnetic resonance sequence in childhood Neuroblastoma, Wilḿ s tumor, Lymphoma, and Hepatoblastoma, helping providing additional information to differentiate high cellularity tumors from others, as well as reducing ionizing radiation exposure, adding another tool for diagnostic imaging, especially in this age group patients.

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MRI in Pediatric Oncology, Abdominal Tumors: Diffusion

Schiavon

Pioner

Lederman

2014

Curr Radiol Rep

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MRI Evaluation of Pediatric Malignant Abdominal Tumors

et al. 2015

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Mostly, pediatric abdominal tumors are benign. Eventually, malignant cancer may occur as abdominal tumor being the Wilms tumor, neuroblastoma, hepatoblastoma, and Burkitt's lymphoma found to be common on this age group. Abdominal tumors can have a wide etiology range that can be classified according to its location, age group, and associated signs and symptoms. Mostly, benign findings are hydronephrosis, infectious hepatosplenomegaly, and ascariasis, while neuroblastoma, Wilms tumor, and germ cell tumors can exhibit specific MRI findings helping on its determination. This article discuss some clinical and MRI presentation of main abdominal pediatric malignances, as well as imaging findings that can correlate to clinical aspects to help during staging and patients' treatment follow up.

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Radiology's Role in the Battle against Pediatric Cancers

Cited by 2 publications

References 6 publications

MRI in Pediatric Oncology, Abdominal Tumors: Diffusion

MRI in Pediatric Oncology, Abdominal Tumors: Diffusion

MRI Evaluation of Pediatric Malignant Abdominal Tumors

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