Radiolysis of pyrimidines in aqueous solutions. Part 2.—Product formation in the interaction of e–aq, ·H, ·OH and Cl–2· with uracil

Chemical Effects of Tritium Decay in Aqueous Solution of Uracil

“…Table 2 shows the per cent decomposition of uracil and the decomposition G-values, G(-U), under conditions A-D. G(-U) values are higher than 2G('^C)-values (Table 1) since some degradation products were missing in the analyses (vide infra). It is to be noted that all of the G-values reported here are significantly lower than those reported in the literature for gamma-irradiated aqueous solutions of uracil under different experimental conditions [12][13][14][15]. For example, G(-U) for neutral deaerated solutions is between 2.5 and 2.7 [12,13,15], and for air-saturated Solution it is 2.85 [14].…”

“…It is to be noted that all of the G-values reported here are significantly lower than those reported in the literature for gamma-irradiated aqueous solutions of uracil under different experimental conditions [12][13][14][15]. For example, G(-U) for neutral deaerated solutions is between 2.5 and 2.7 [12,13,15], and for air-saturated Solution it is 2.85 [14]. G-values fOr individual radiolytic products were found to lie between 0.1 and 0.7 [12][13][14][15].…”

Ionizing Radiation-Induced Attachment Reactions of Nucleic Acids and Their Components

“…i solutions of thymine, the thymine is converted in less than stoichiometric amounts to compounds with elements of water added to the 5,6-double bond or substituted into the methyl group. Among the products are the hydrate, the glycol, and dihydrothymintf , Infante et al, 1973 Similar products are obtained with uracil (Smith and Hays, 1968).…”

“…This accumulated evidence suggests that further investigation of attachment and related reactions which may be reasonably expected to occur in cells will be an important and critical part of our continuing efforts to understand radiation effects and develop ways to modify them. Teoule, et al, 1972Infante, et al, 1973Smith and Hays, 1968Scholes et al, 1960Karael and Garrison, 1965Kamel and Garrison, 1965Brown, et al, 1966 it Zarebska andShugar, 1972 Elad, et al, 1969 ti Steinmaus, et al, 1969Leonov, et al, 1975 …”

The sonolysis of uracil

“…Uracil absorbance was measured at 259.5nm in a Since the radiolysis of uracil has been exhaus-I.Ocm quartz cell and that of 5-bromouracil at 276nm. A tively investigated (6)(7)(8)(9)(10)(11)(12)(13)(14) and the primary reactions Beckman Expandomatic SS-2 pH meter was used to measure the pH values before and after sonolysis. in the sonolysis of aqueous solutions (15)(16)(17)(18)(19)(20)(21) are known to be essentially similar to those produced in cenera~ A~~I~~~~ Procedures radiolytic reactions, the sonolysis and radiolysis After lyophilization the degradation products were converted results are compared and contrasted.…”