Radionuclide candidates for β+γ coincidence PET: An overview

Sitarz, Mateusz; Cussonneau, J. P.; Matulewicz, T.; Haddad, Férid

doi:10.1016/j.apradiso.2019.108898

Cited by 43 publications

(42 citation statements)

References 230 publications

(277 reference statements)

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“…The value of sensitivity is given in arbitrary units, however the values in the left and right figures are shown in the same scale. 44 Sc or 82 Rb. The single-layer J-PET prototype with AFOV 5 50 cm weighs only approximately 60 kg.…”

Section: Prospects For Total-body Pet Imaging With Plastic Scintillatorsmentioning

confidence: 99%

“…[27][28][29] In the right panel only the results obtained for the total-body imaging (for source of L 5 200 cm) are shown. Calculations were performed assuming energy of the prompt gamma of 1157 keV as emitted by the 44 Sc isotope. 44 as well as the changes of interaction probability as a function of the angle under which the photon is entering the detector.…”

Section: Sensitivity Gainmentioning

confidence: 99%

“…Calculations were performed assuming energy of the prompt gamma of 1157 keV as emitted by the 44 Sc isotope. 44 as well as the changes of interaction probability as a function of the angle under which the photon is entering the detector. The attenuation was estimated approximating the body with a water phantom of 20 cm diameter and 200 cm long.…”

Section: Sensitivity Gainmentioning

confidence: 99%

“…37 This may include selection of double, triple and in general multicoincidence events. In particular it enables registration and identification of 2 (e 1 e À / 2g) and 3 photon (e 1 e À / 3g) annihilations, as well as prompt gamma emitted in case of some isotopes referred to as b 1 g emitters, such as for example, 10 C, 14 O, 22 Na, 34 Cl, 44 Sc, 48 V, 52 Mn, 55 Co, 60 Cu, 66 Ga, 69 Ge, 72 As, 76 Br, 82 Rb, 86 Y, 94 Tc, 110 In, 124 I. 44 Some examples of multiphoton events are shown pictorially in the right panel of Fig.…”

Section: Multiphoton Imagingmentioning

confidence: 99%

“…The daughter nucleus subsequently de-excites through emission of 1 or several gamma quanta. For example, in the case of Scandium the reaction chain is as follows: 44 Sc / 44 Ca* e 1 v / 44 Ca g e 1 v, where v denotes neutrino that escapes from the body undetected.…”

Section: Multiphoton Imagingmentioning

confidence: 99%

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Prospects and Clinical Perspectives of Total-Body PET Imaging Using Plastic Scintillators

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Total-body PET opens a new diagnostic paradigm with prospects for personalized disease treatment, yet the high cost of the current crystal-based PET technology limits dissemination of totalbody PET in hospitals and even in the research clinics. The J-PET tomography system is based on axially arranged low-cost plastic scintillator strips. It constitutes a realistic cost-effective solution of a total-body PET for broad clinical applications. High sensitivity of total-body J-PET and triggerless data acquisition enable multiphoton imaging, opening possibilities for multitracer and positronium imaging, thus promising quantitative enhancement of specificity in cancer and inflammatory diseases assessment. An example of dual tracer analysis, becoming possible with total-body J-PET system, could be a concurrent application of Food and Drug Administration-approved 82 Rb-Chloride and [ 18 F]FDG, allowing simultaneous assessment of myocardium metabolic rate and perfusion of the cardiovascular system.

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Section: Prospects For Total-body Pet Imaging With Plastic Scintillatorsmentioning

confidence: 99%

Section: Sensitivity Gainmentioning

confidence: 99%

Section: Sensitivity Gainmentioning

confidence: 99%

Section: Multiphoton Imagingmentioning

confidence: 99%

Section: Multiphoton Imagingmentioning

confidence: 99%

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Prospects and Clinical Perspectives of Total-Body PET Imaging Using Plastic Scintillators

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Nanoradiopharmaceuticals: An Attractive Concept in Oncotherapy

Hou,

Liu,

2024

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Radiopharmaceuticals are of significant importance in the fields of tumor imaging and therapy. In recent decades, the increasing role of nanotechnology has led to the attractive concept of nanoradiopharmaceuticals. Consequently, it is imperative to provide a concise summary of the necessary guidelines to facilitate the translation of nanoradiopharmaceuticals. In this work, we have presented the contents of radiolabeling strategies and some applications of nanoradiopharmaceuticals. Such a framework can assist researchers in identifying more pertinent insights or making more informed decisions in the study of nanoradiopharmaceuticals.

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Electrochemical deposition of nickel targets from aqueous electrolytes for medical radioisotope production in accelerators: a review

Mieszkowska

Grdeń

2021

J Solid State Electrochem

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This paper reviews reported methods of the electrochemical deposition of nickel layers which are used as target materials for accelerator production of medical radioisotopes. The review focuses on the electrodeposition carried out from aqueous electrolytes. It describes the main challenges related to the preparation of suitable Ni target layers, such as work with limited amounts of expensive isotopically enriched nickel; electrodeposition of sufficiently thick, smooth and free of cracks layers; and recovery of unreacted Ni isotopes from the irradiated targets and from used electrolytic baths.

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Radionuclide candidates for β+γ coincidence PET: An overview

Abstract: This paper summarizes the properties, applications and feasible production of all known radioisotopes that can be used in the novel β+γ coincidence PET technique. These radioisotopes include:

Cited by 43 publications

References 230 publications

Prospects and Clinical Perspectives of Total-Body PET Imaging Using Plastic Scintillators

Prospects and Clinical Perspectives of Total-Body PET Imaging Using Plastic Scintillators

Nanoradiopharmaceuticals: An Attractive Concept in Oncotherapy

Electrochemical deposition of nickel targets from aqueous electrolytes for medical radioisotope production in accelerators: a review

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