Radionuclides in the evaluation of urinary obstruction

Scharf, Stephen C.; Blaufox, M. Donald

doi:10.1016/s0001-2998(82)80040-8

Cited by 14 publications

(3 citation statements)

References 25 publications

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“…2Y4 However, it is simple, less time-consuming, 26 and more suitable and convenient in following the patient's renal function. 5,27 The captopril renography even plays an important role in the diagnosis of renal insufficiency, small kidneys, and bilateral renal artery disease. 28 For these reasons, most scanner vendors provide the program in available commercial workstations.…”

Section: Discussionmentioning

confidence: 99%

Lean Body Mass Is Better Than Body Surface Area in Correcting GFR

Si¹,

Lei²,

Li³

et al. 2013

Clinical Nuclear Medicine

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Section: Discussionmentioning

confidence: 99%

Lean Body Mass Is Better Than Body Surface Area in Correcting GFR

Si¹,

Lei²,

Li³

et al. 2013

Clinical Nuclear Medicine

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“…Time-activity curves drawn from whole kidney ROI look similar. Abnormal renograms generated from the cortical ROI are considered by some as a definite sign of true obstruction, but this notion remains controversial [27].…”

Section: Diuretic Renographymentioning

confidence: 99%

Advances in radionuclide evaluation of urinary tract obstruction

Dubovsky

Russell

1998

Abdom Imaging

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“…Since its introduction, dynamic radionuclide renal imaging has sought to provide a reliable means of diagnosing and documenting the progress of urinary tract obstruction. Many approaches have been tested and the diuretic renogram using 99mTc DTPA has been described as a useful method for determining urinary tract obstruction (Scharf and Blaufox, 1982). Studies of 99mTc DTPA diuretic renography have also included its use in children (Ash et al, 1982), where a high diagnostic success rate has been claimed (O'Reilly et al, 1979).…”

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confidence: 99%

^99mTc DTPA Scanning with Diuretic Washout. Is it Useful in the Investigation of Obstruction in the Presence of Gross Renal Tract Dilatation?

Hunter

Gordon

Sweeney

et al. 1987

British Journal of Urology

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Diuretic-enhanced 99mTc DTPA renal scanning aims to determine whether or not a kidney is obstructed. In the presence of gross renal tract dilatation the validity of this technique is questioned. Twenty-eight patients (51 kidneys) with the prune belly syndrome, characterised by gross dilatation and tortuosity of the ureters, were studied. These patients underwent diuretic 99mTc DTPA scanning at the time of diagnosis and at yearly intervals thereafter. Long-term clinical follow-up (3 years) with serial serum creatinine was available in all children. In all cases renal function remained stable and on this basis urinary tract obstruction was excluded. Analysis of the first 99mTc DTPA scan included differential function, whole kidney mean transit time (WKMTT) and the time taken for tracer activity to fall to 75% of peak activity after diuretic stimulus (T75). Using the 99mTc DTPA scan, obstruction can be excluded if the WKMTT is less than 5 min or, in the presence of a prolonged WKMTT, if the diuretic stimulus results in a T75 of less than 5 min. A T75 of between 5 and 10 min is considered equivocal and a T75 exceeding 10 min means that obstruction cannot be excluded. 99mTc DTPA scanning, using these criteria for diagnosis, provided false positive information in 22 kidneys (43%). There were no false negatives. 99mTc DTPA scanning with diuretic washout, using WKMTT and T75 criteria, is not appropriate for the detection of renal tract obstruction in the presence of marked upper renal tract dilatation, since the false positive rate of 43% is unacceptably high.

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Radionuclides in the evaluation of urinary obstruction

Cited by 14 publications

References 25 publications

Lean Body Mass Is Better Than Body Surface Area in Correcting GFR

Lean Body Mass Is Better Than Body Surface Area in Correcting GFR

Advances in radionuclide evaluation of urinary tract obstruction

^99mTc DTPA Scanning with Diuretic Washout. Is it Useful in the Investigation of Obstruction in the Presence of Gross Renal Tract Dilatation?

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