Abstract:Sclareolide is an active ingredient from clary sage. 8 Sclareolide inhibits TRPV1 and TRPV4, 8 which are involved in sensitive skin. 9 Our study has some limitations, mainly the absence of a control group. Nonetheless, the tested cream showed efficacy on sensitive skin symptoms as well as a significant improvement in the thresholds of cutaneous sensitivity to heat.
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