Radiotherapy of skin cancer

Chemoradiation using low-dose cisplatin and 5-fluorouracil in locally advanced squamous cell carcinoma of the skin: A report of two cases

“…9 However, the control rate of radiotherapy for tumors exceeding 5 cm in diameter is poor. 10 Shiu, Chu, and Fortner 11 reported that only 1 in 15 patients with advanced SCC of the skin showed complete response by radiotherapy alone. On the other hand, several reports showed that some combinations of chemotherapy regimens were effective in treating advanced cases: cisplatin 1 doxorubicin, 12 cisplatin 1 5-fluorouracil, 13 and cisplatin 1 interferon alfa 1 retinoic acid.…”

Squamous cell carcinoma of the skin: clinical presentation, diagnosis, treatment, and prevention

“…При стадиях Т3 и Т4 лучевую тера-пию используют в качестве пред-и послеопераци-онного лечения, однако у 1 / 4 больных в последую-щем развивается рецидив ПКРК, который уже будет резистентный к повторным курсам лучевой терапии [22].…”

“…Недостатки метода: возможно развитие луче-вых периоститов, перихондритов костей черепа, но-са, хрящей ушной раковины, а также конъюнктиви-та, катаракты, неудовлетворительных в косметиче-ском отношении рубцовых деформаций [22][23][24].…”

Office Radiotherapy of Cutaneous Carcinomas

“…Fischbach et al 28 treated 87 cancers of the nose in a radiation oncology department; 7 recurred after a total dose of 4,000 rad. The authors emphasized that cartilage necrosis was not a significant problem.…”

“…Fischbach et al 28 treated 32 carcinomas of eyelids in a radiation oncology department and observed only 1 recurrence after a total dose of 4,000 rad. Contracture of an eyelid occurred in one recurrent carcinoma previously treated by surgery.…”