Radiotherapy with or without Concomitant Chemotherapy as Pre- or Postoperative Therapy in Non-small Cell Lung Cancer

Abstract

Recently, it has been shown that even in patients with unresectable stage III, a short course of cisplatin and vinblastine prior to radiation significantly improved median survival and doubled the number of long-term survivors, as compared with radiation therapy alone [2]. Our hypothesis was that tri modality therapy for lung cancer will

Endobronchial Ultrasound to Evaluate Downstaging of Lung Cancer After Combined Chemotherapy and Radiation Treatment

“…1 Several other studies and clinical trials that were subsequently radiotherapy in the management of NSCLC. 2 While previous studies did indeed advance novel treatment methods for NSCLC, the team in Bangkok Hospital found it curious that even in a recent study published in April 2012, 3 the most advanced staging evaluation methods used were mediastinoscopy or mediastinotomy (following bronchoscopy, bone scan, computed tomography (CT) scan of the chest) to acquire biopsy samples from lymph nodes. A randomized trial in 2010 of two-hundred and forty one patients revealed that a staging strategy combining endosonography and surgical staging showed a higher sensitivity rate for mediastinal nodal metastases when compared to surgical staging alone among patients with (suspected) NSCLC.…”