Radiumbestrahlung unbefruchteter Froscheier und ihre Entwicklung nach Befruchtung mit normalem Samen

Hertwig, Günther

doi:10.1007/bf02997376

Cited by 66 publications

(4 citation statements)

References 17 publications

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“…Investigators have used ages rather than stages to describe their results and in using such a unit as daysdevelopment, temperature variations become important. Among species of frogs, the androgenetic development described by G. Hertwig (1911) for R. fusca and by Dalcq (1932) for R. esculenta is no more successful than that reported here for R. pipiens. In fact, as far as uniformity is concerned, the results with R. pipiens seem to be better.…”

Section: The Extent and Uniformity Of Developmentcontrasting

confidence: 60%

“…inactive by radium emanations and x-rays (G. Hertwig, 1911Hertwig, , 1913Hertwig, , 1927P. Hertwig, 1916P.…”

Section: Methodsmentioning

confidence: 99%

“…It is, therefore, not surprising that the amphibian egg has been generally used. G. Hertwig, in 1911, treated the eggs of Rana fusca with radium emanations, then fertilized them, and obtained androgenetic development for what appears to be the first time. Since then a variety of methods have been used to remove or inactivate the egg nucleus (see below).…”

Section: Introductionmentioning

confidence: 99%

“…Since then a variety of methods have been used to remove or inactivate the egg nucleus (see below). These have been applied to various European species of frogs (G. Hertwig, 1911;P. Hertwig, 1923;Dalcq, 1932) and toads (G. Hertwig, 1913;P.…”

Section: Introductionmentioning

confidence: 99%

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Androgenetic Development of the Egg of Rana Pipiens

Porter¹

1939

The Biological Bulletin

132

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Section: The Extent and Uniformity Of Developmentcontrasting

confidence: 60%

“…inactive by radium emanations and x-rays (G. Hertwig, 1911Hertwig, , 1913Hertwig, , 1927P. Hertwig, 1916P.…”

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Androgenetic Development of the Egg of Rana Pipiens

Porter¹

1939

The Biological Bulletin

132

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Stimulation and Immunity in Radiotherapy

Desjardins¹

1926

JAMA

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Disturbances in mammalian development produced by radium emanation

Bagg

1922

Am. J. Anat.

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The effects of radium on animal development has been the subject of several researches since the early work of Bohn (l), in 1903, upon the ova and larvae of the sea-urchin. Experiments on developing nematodes, molluscs, amphibians, fishes, and birds are associated with the names of Perthes (a), P. Hertwig (3), Schaper (4), 0. Hertwig ( 5 ) , and G. Hertwig (6). These investigators report developmental retardations following radiation of the ova and developing embryos. They found a particular susceptibility of the nuclei of the cells and a general slowing up in the developmental processes, especially in the case of the central nervous system. The total disturbances, depending upon the period of development when the radiation was applied, resulted in the formation of monstrosities conforming more or less to a general type.1 Similar experiments concerning the effects of x-rays on development have been conducted by many investigators. After exposure to x-radiation, Perthes (7) noted abnormal cell divishi and a retardation in the development, of the ova of lZscaris mega-1 I n connection with the above statement,, and applying to x-ray trcotments as well, the question of dosage is an important one. A survey of the literature shon-s t h a t there was a very wide range in the severity of the dose employed, and in several cases the experimental settings were inadequately described (Bohn used 'some ccntigrams' of pure radium bromide for from twenty minutes to two hours!. The amount of radium metal used in the investigations t h a t have been mentioned varied from 2 mg. to 35.1 mg., and the time from a few seconds to several hours. The deleterious changes in the animal tissues varied with the amount of radium and the time of exposure.

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Radiumbestrahlung unbefruchteter Froscheier und ihre Entwicklung nach Befruchtung mit normalem Samen

Cited by 66 publications

References 17 publications

Androgenetic Development of the Egg of Rana Pipiens

Androgenetic Development of the Egg of Rana Pipiens

Stimulation and Immunity in Radiotherapy

Disturbances in mammalian development produced by radium emanation

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