The arid and semi-arid regions of northwest China are characterized by sparse vegetation and fragile ecosystems, making them highly susceptible to the impacts of climate change and human activities. Based on observed meteorological data, the Normalized Difference Vegetation Index (NDVI), the Lund–Potsdam–Jena dynamic global vegetation model (LPJ), a vegetation recovery potential model, and the MK trend test method, this study investigated the spatiotemporal distribution of vegetation recovery potential in northwest China and its relationship with global warming and increasing precipitation. The results indicated that vegetation in northwest China significantly increased, with greening closely related to trends in warming and wetting during 1982–2019. However, the vegetation recovery potential declined due to climate change. Central and southern Xinjiang and central Qinghai exhibited higher grassland recovery potential, while the central Gobi Desert areas of northwest China had lower recovery potential. The eastern part of northwest China was highly sensitive to drought, with moderate vegetation growth and recovery potential. Remote sensing data indicated a 2.3% increase in vegetation coverage in the region, with an average vegetation recovery potential index (IVCP) of 0.31. According to the results of LPJ model, the average vegetation recovery potential index for northwest China was 0.14, indicating a 1.1% improvement potential in vegetation coverage. Overall, climate warming and wetting facilitated vegetation recovery in northwest China, particularly in mountainous areas. The findings provide valuable insights for ecological restoration efforts and offer practical guidance for combating desertification and enhancing sustainable development. Moreover, these results underline the importance of incorporating vegetation recovery potential into regional policy-making to improve environmental resilience in the face of ongoing climate change.