Brazilian biomes are home to a significant portion of the world's biodiversity, with a total of 14% of existing species and still concentrate 20% of the world's water resources. However, changes in biomes have a direct impact on rainfall patterns and water recycling. Based on this, the objective was to evaluate the variability of rainfall in the four existing biomes in the Northeast Brazil (NEB) and their interaction with the ENSO climate variability mode and regional scale meteorological systems via CHELSA product. For this, monthly rainfall data were used from 1979 to 2013, with a spatial resolution of 1 km × 1 km of the CHELSA product, and seasonal and annual rainfall patterns were extracted via boxplot. It was found that the rainy season in the Amazon, Caatinga and Cerrado biomes occurred between January and April, with varying intensities, except for the Atlantic Forest. Such seasonality patterns are associated with the NEB meteorological systems, with emphasis on ITCZ (all Biomes), UTCV (Amazon, Caatinga and Cerrado), Frontal Systems (extreme south of Caatinga, Cerrado and Atlantic Forest) and EWD/ TWD in the (Atlantic Forest). In the inter-annual scale, the remarkable influence of ENSO was verified,