Ralstonia mannitolilytica sepsis after elective cesarean delivery: a case report

Abstract

Background Ralstonia mannitolilytica, a newly emerging opportunistic pathogen worldwide, has been reported to be responsible for human pneumonia, septicemia and meningitis. This is the first report of a case of Ralstonia mannitolilytica sepsis after elective cesarean delivery. Case presentation A 25-year-old woman, gravida 1 para 0, was scheduled for an elective cesarean delivery at 39+ 1 weeks of gestation. Sudden high fever and decreased blood pressure occurred a short time after the operation. Ralstonia mannitolilytica was identified in her blood culture 5 days after the operation. Based on the presence of sepsis and septic shock, massive fluid replacement, blood transfusion, vasoactive agents, imipenem/cilastatin and cefoperazone sulbactam sodium were applied. She was discharged after intensive care without complications. Conclusions Although the incidence of sepsis due to Ralstonia mannitolilytica is relatively low, once infection occurs in a puerpera, severe symptoms develop abruptly. Thus, prompt diagnosis and appropriate treatment are key to the cure.

Spherical pneumonia caused by Ralstonia mannitolilytica: a case report and literature review

“…There are few national and international reports, and there are current case reports of cystic fibrosis with infection, elderly hospital-acquired pneumonia, bronchiectasis, chronic obstructive pulmonary disease, bacteremia, solid cancer, abdominal dialysis tube infection, neonatal, hematologic, renal transplantation, diabetes mellitus, scleroderma, meningitis, peritonitis, osteomyelitis, abdominal blood collection infection, and urinary tract infection. Elderly patients, those with multiple underlying diseases, those using broad-spectrum antibacterial drugs, and those receiving invasive mechanical ventilation are at an increased risk of infection with this organism [ 32 , 34 – 45 ]. Although previous reports showed that the infection caused by R. mannitolilytica is more common in immunocompromised groups, the report of R. mannitolilytica infection in the normal immunity population is rare, and the specific mechanism is still unclear.…”

Ralstonia mannitolilytica: an emerging multidrug-resistant opportunistic pathogen in a tertiary care hospital setting

“…R. mannitolilytica are known to cause sepsis, meningitis and central venous catheterassociated bacteraemia [3]. Of late several case reports of infections by R. mannitolilytica have been seen from India and worldwide [4][5][6][7][8][9][10][11][12]. Many case reports have highlighted R. mannitolilytica as causing bacteraemia and sepsis [4][5][6][7][8][9][10][11].…”

“…Of late several case reports of infections by R. mannitolilytica have been seen from India and worldwide [4][5][6][7][8][9][10][11][12]. Many case reports have highlighted R. mannitolilytica as causing bacteraemia and sepsis [4][5][6][7][8][9][10][11]. Lampropoulos et al (2021) and Rajendran et al (2022) highlighted the organism as an emerging opportunistic pathogen causing sepsis in neonatal intensive care units [9,10] .…”

“…Of late several case reports of infections by R. mannitolilytica have been seen from India and worldwide [4–12]. Many case reports have highlighted R.…”

“…Many case reports have highlighted R. mannitolilytica as causing bacteraemia and sepsis [4–11]. Lampropoulos et al (2021) and Rajendran et al (2022) highlighted the organism as an emerging opportunistic pathogen causing sepsis in neonatal intensive care units [9, 10] .…”