Raman spectroscopy and Raman optical activity of blood plasma for differential diagnosis of gastrointestinal cancers

Kralova, Katerina; Vrtelka, Ondrej; Fouskova, Marketa; Hribek, Petr; Bunganic, Bohus; Miskovicova, Michaela; Urbanek, Petr; Zavoral, Miroslav; Petruzelka, Lubos; Habartova, Lucie; Setnicka, Vladimir

doi:10.1016/j.saa.2023.123430

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

2024

DOI: 10.1016/j.saa.2023.123430

|View full text |Cite

Raman spectroscopy and Raman optical activity of blood plasma for differential diagnosis of gastrointestinal cancers

Katerina Kralova,

Ondrej Vrtelka,

Marketa Fouskova

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article3

Relationship

Self Cite0

Independent3

Authors

Journals

Cited by 3 publications

References 60 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Application of an interpretable Raman-Spectral classification model based on a transposed convolution and attention mechanism to tumor-tissue screening

Wan,

Wang,

Liu

et al. 2024

Applied Soft Computing

View full text Add to dashboard Cite

Application of an interpretable Raman-Spectral classification model based on a transposed convolution and attention mechanism to tumor-tissue screening

Wan,

Wang,

Liu

et al. 2024

Applied Soft Computing

View full text Add to dashboard Cite

Navigating the future of ROA: Can it surprise us?

Lightner,

Kaczor,

Johannessen

2024

Vibrational Spectroscopy

View full text Add to dashboard Cite

Cumulative Distribution Function and Spatially Resolved Surface-Enhanced Raman Spectroscopy for the Quantitative Analysis of Emtricitabine

Hrncirova,

Butler,

Dutta

et al. 2024

Applied Spectroscopy Practica

View full text Add to dashboard Cite

Surface-enhanced Raman spectroscopy (SERS) has exceptional analytical sensitivity and selectivity. However, SERS irreproducibility presents an obstacle when using it for precise quantitative measurements. In this study, colloidal nanoparticles evaporated to dryness are used as a SERS active surface for the detection of the HIV drug emtricitabine (FTC; trade name Emtriva). Despite the irreproducibility of the SERS resulting from the stochastic process of evaporation, using a SERS scanning instrument, the SERS enhancement factors of spatially resolved spectra have a well-defined distribution of signals for a given analyte concentration. This distribution follows a power law function ranging from weak (very abundant signals) to very strong (sparse signals). By definition, a power law distribution cannot have a true mean. Hence a cumulative distribution function was used to model the concentration of emtricitabine, and calibration curves were constructed. For stochastically generated quantitative data sets, the precision of this approach is superior to methods utilizing signal averaging and improves analytical sensitivity.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Raman spectroscopy and Raman optical activity of blood plasma for differential diagnosis of gastrointestinal cancers

Cited by 3 publications

References 60 publications

Application of an interpretable Raman-Spectral classification model based on a transposed convolution and attention mechanism to tumor-tissue screening

Application of an interpretable Raman-Spectral classification model based on a transposed convolution and attention mechanism to tumor-tissue screening

Navigating the future of ROA: Can it surprise us?

Cumulative Distribution Function and Spatially Resolved Surface-Enhanced Raman Spectroscopy for the Quantitative Analysis of Emtricitabine

Contact Info

Product

Resources

About