Ramelteon in the Prophylaxis of Chronic Cluster Headache- Case Report

Hamada, Yukihiro; Saigoh, Kazumasa; Mitsui, Yosuke; Takeshima, Takao; Kusunoki, Susumu

doi:10.17554/j.issn.2313-5611.2015.01.7

Cited by 1 publication

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“…A few reports from Japan have suggested that ramelteon immediately suppressed cluster headache attacks during sleeping and showed no adverse effects. [29][30][31]…”

Section: Ramelteonmentioning

confidence: 99%

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Cluster headache and trigeminal autonomic cephalalgias: Recent advances in diagnosis and management

Imai

2019

Neurology & Clinical Neurosc

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Trigeminal autonomic cephalalgias (TACs) are a group of primary headache disorders characterized by unilateral distribution of trigeminal pain that occurs in association with prominent ipsilateral cranial autonomic features. TACs include cluster headache, paroxysmal hemicrania, short-lasting unilateral neuralgiform headache attacks, and hemicrania continua. The severity of these disorders has major effects on quality of life. Early diagnosis and appropriate management can thus markedly improve quality of life for the patient. Subcutaneous sumatriptan and pure oxygen inhalation are the most effective abortive therapies for acute cluster headache. Home oxygen therapy (HOT) has been covered by health insurance in Japan since 2018. Several drugs, such as verapamil and prednisolone, are effective in reducing the frequency of attacks in patients with cluster headache. Calcitonin gene-related peptide monoclonal antibodies and non-invasive vagus nerve stimulation are new treatments that have proven effective against cluster headache. Patients with paroxysmal hemicrania and hemicrania continua show absolute positive responses to indomethacin. Lamotrigine and several other anticonvulsants are effective in reducing the frequency of attacks in patients with short-lasting unilateral neuralgiform headache. K E Y W O R D S calcitonin gene-related peptide, indomethacin, monoclonal antibodies, non-invasive vagus nerve stimulation, trigeminal autonomic cephalalgias How to cite this article: Imai N. Cluster headache and trigeminal autonomic cephalalgias: Recent advances in diagnosis and management.

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“…A few reports from Japan have suggested that ramelteon immediately suppressed cluster headache attacks during sleeping and showed no adverse effects. [29][30][31]…”

Section: Ramelteonmentioning

confidence: 99%

“…Ramelteon is a selective melatonin receptor agonist and a member of a new class of insomnia medications. A few reports from Japan have suggested that ramelteon immediately suppressed cluster headache attacks during sleeping and showed no adverse effects …”

Section: Managementmentioning

confidence: 99%

Cluster headache and trigeminal autonomic cephalalgias: Recent advances in diagnosis and management

Imai

2019

Neurology & Clinical Neurosc

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show abstract

Ramelteon in the Prophylaxis of Chronic Cluster Headache- Case Report

Cited by 1 publication

References 9 publications

Cluster headache and trigeminal autonomic cephalalgias: Recent advances in diagnosis and management

Cluster headache and trigeminal autonomic cephalalgias: Recent advances in diagnosis and management

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