Randomised controlled trial of continuous positive airway pressure and standard oxygen therapy in acute pulmonary oedema. Effects on plasma brain natriuretic peptide concentrations

Abstract

CPAP produces a more rapid clinical and symptomatic improvement in patients with acute pulmonary oedema, particularly within the first hour. CPAP is a useful adjunctive treatment in the early management of acute heart failure.

Bi-level Versus Continuous Positive Airway Pressure in Acute Cardiogenic Pulmonary Edema: A Randomized Control Trial

“…An improvement in RR and symptoms of respiratory fatigue (improved breathing pattern, decreasing intercostal suprasternal retraction and subjective respiratory distressed) when coupled with improved oxygenation, and lower PaCO 2 is considered as indirect objective evidence of decrease work of breathing, dyspnea, and alveolar hypoventilation [15,31]. These confirm that the therapeutic intervention in our study was delivered successfully and appropriately.…”

Noninvasive Positive Pressure Ventilation: Resource Document for the National Association of EMS Physicians Position Statement

“…1,[5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22] The benefits of inhospital NIPPV have been confirmed through metaanalyses. In a systematic review and meta-analysis of NIPPV in acute cardiogenic pulmonary edema, Masip et …”

“…The majority of NIPPV studies have focused on patients with acute pulmonary edema. [6][7][8][9]11,[13][14][15][16][17][18][19][20][21][22][23][24][25][26]29,31,32,35,[38][39][40][41] However, NIPPV may prove useful with other reversible disease processes such as chronic obstructive pulmonary disease or asthma exacerbations. 33,42,43 While utilized in in-hospital practice, the role of NIPPV for pneumonia-associated respiratory failure is less clear.…”

Current treatment options for early management in acute decompensated heart failure

“…This is supported by one study (3) that showed noninvasive positive pressure ventilation therapy was associated with worse outcomes when given in preference to vasodilator therapy. None of these slightly different types of assisted ventilation have been shown to be superior to any other and studies of these modalities are ongoing (4)(5)(6)(7). These therapies should be considered primarily when the patient is hypoxic with SaO 2 of less than 90% (5).…”