Randomised controlled trials addressing Australian Aboriginal health needs: A systematic review of the literature

Ps, Morris

doi:10.1046/j.1440-1754.1999.t01-1-00341.x

Cited by 23 publications

(8 citation statements)

References 34 publications

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“…4 Staff struggle to address basic health needs. Most remote communities are small, limiting sample sizes, yet these are where the needs may be greatest.…”

Section: Discussionmentioning

confidence: 99%

Antistreptokinase antibodies: implications for thrombolysis in a region with endemic streptococcal infection: Table 1

Blackwell

Hollins²,

Gilmore³

et al. 2005

J Clin Pathol

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Aims:To determine antistreptokinase antibody (anti-SK) titres in patients with the acute coronary syndrome from communities with endemic group A streptococcal infection because of the implications for streptokinase (SK) thrombolysis.Methods:Anti-SK titres were determined using a standard method in 47 consecutive SK naive patients, presenting to the Mt Isa Hospital emergency department, Australia, with an acute coronary syndrome. Both indigenous and non-indigenous subjects were enrolled. Antistreptolysin O (ASOT) and anti-DNAse B (ADB) titres were also determined.Results:Indigenous patients were more likely to have anti-SK antibodies (p < 0.001) than the non-indigenous cohort. Anti-SK antibody titres also correlated well with ASOT/ADB titres.Conclusions:Anti-SK antibodies are highly prevalent in SK naive indigenous patients presenting with the acute coronary syndrome. Streptokinase should not be used for thrombolysis in populations with endemic group A streptococcal infection.

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“…4 Staff struggle to address basic health needs. Most remote communities are small, limiting sample sizes, yet these are where the needs may be greatest.…”

Section: Discussionmentioning

confidence: 99%

Antistreptokinase antibodies: implications for thrombolysis in a region with endemic streptococcal infection: Table 1

Blackwell

Hollins²,

Gilmore³

et al. 2005

J Clin Pathol

View full text Add to dashboard Cite

show abstract

“…Many types of participative research have been described (Israel et al 1998) but few studies have documented how community control is applied by Indigenous groups. Community-based research involving the Australian Aboriginal population remains mostly descriptive: there are few controlled clinical trials (Morris 1999) and a focus on identifying solutions to health problems is lacking (Atkinson et al 2002).…”

Section: Introductionmentioning

confidence: 99%

‘We are Not Just Participants—We are in Charge’: The NACCHO Ear Trial and the Process for Aboriginal Community-controlled Health Research

Couzos¹,

Lea²,

Murray³

et al. 2005

Ethnicity & Health

108

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The 22 methodological elements which defined the community-controlled design of the ear trial may assist community groups, external research bodies and funding agencies to improve the acceptability, quality and scope of research involving Indigenous peoples. Aboriginal community-controlled organisations are well placed to lead research, which can be interventional and of a high scientific standard without compromising the values and principles of those being researched. With over 120 Aboriginal community-controlled health services (ACCHSs) across Australia, the potential exists for these services to engage in multi-centre research to realise solutions to health problems faced by Indigenous Australians.

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“…First, although Indigenous-specific alcohol treatment guidelines [6][7][8][9] and resources [10][11][12][13] are currently available, their uptake by healthcare providers delivering healthcare to Indigenous Australians is less than optimal [14,15]. Second, a lack of methodologically rigorous alcohol intervention trials in Indigenous settings limits the amount and quality of evidence available to inform the implementation of alcohol interventions in Indigenous communities [15][16][17]. Third, there is an inevitable delay between intervention research effort and the dissemination of cost-effective strategies [18].…”

Section: Introductionmentioning

confidence: 99%

The Dissemination of Alcohol Interventions for Indigenous Australians: A Mixed Studies Review Using Narrative Synthesis

Whitty¹,

Clifford²

2017

J Alcohol Drug Depend

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Issues: Indigenous Australians experience disproportionately high rates of alcohol related harms. The implementation of best evidence alcohol interventions to reduce these harms is therefore a priority. This review synthesises evidence from the peer reviewed literature on factors influencing implementation. Approach:A systematic appraisal of journal articles based on alcohol-related harm reduction interventions for Indigenous Australians with scope for dissemination. This involved a systematic database search, categorisation, data extraction, quality appraisal, and preliminary analysis. A thorough textual analysis of identified papers was carried out using narrative synthesis. Key findings:Thirteen publications met the inclusion criteria. Included studies assessed either: (a) Acceptability/ feasibility of alcohol interventions for implementation in Indigenous-specific healthcare settings and/or delivery to Indigenous Australians (n=7); (b) The effectiveness of strategies designed to improve the uptake/delivery of an alcohol intervention (n=4); or (c) The process of implementing an alcohol intervention with Indigenous Australians (n=2).Implications: Flexibility in study implementation, an emphasis on capacity building and prioritising the reporting of implementation evidence is needed. Conclusion:Overall, the number of dissemination studies focusing on alcohol interventions for Indigenous peoples is low, and their quality varied. Evidence detailing the circumstances for optimal implementation of such interventions is thin, despite the value of this information to future research. This review presents knowledge gained to date on the alcohol interventions considered appropriate and practicable for Indigenous people. Future efforts should reflect greater researcher reflexivity and implementation transparency, and extend measurement of outcomes to health considerations determined to be meaningful by the affected Indigenous people themselves.

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Randomised controlled trials addressing Australian Aboriginal health needs: A systematic review of the literature

Abstract: There is a profound lack of well-designed studies assessing medical interventions. This is further evidence that Australia has failed to develop a research infrastructure able to inform health care in Aboriginal communities. Adults appear especially disadvantaged.

Cited by 23 publications

References 34 publications

Antistreptokinase antibodies: implications for thrombolysis in a region with endemic streptococcal infection: Table 1

Antistreptokinase antibodies: implications for thrombolysis in a region with endemic streptococcal infection: Table 1

‘We are Not Just Participants—We are in Charge’: The NACCHO Ear Trial and the Process for Aboriginal Community-controlled Health Research

The Dissemination of Alcohol Interventions for Indigenous Australians: A Mixed Studies Review Using Narrative Synthesis

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