Randomized clinical trial of laparoscopic <i>versus</i> open fundoplication: blind evaluation of recovery and discharge period

Nilsson, Gustav; Larsson, Sven; Johnsson, Folke

doi:10.1046/j.1365-2168.2000.01471.x

Cited by 131 publications

(70 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The mean preoperative quality of life score was 32.34 6 4.28 (22-38); postoperatively, the average value of this score decreased to 4.76 6 0.92 (3)(4)(5)(6). In the postoperative period, GERD-HRQL scores were significantly decreased compared to the preoperative period (P ¼ 0.001).…”

Section: Resultsmentioning

confidence: 77%

“…With the development of laparoscopic antireflux surgery, reductions have been achieved in morbidity, mortality and even in the rate of recurrence of surgical treatment. 6 Moreover, although successful results of laparoscopic antireflux surgery have been reported, the limited number of studies comparing surgical and medical treatment has prevented resolution of this debate. Given the prognosis of the disease, the incidence of complications is also increasing with the severity of disease.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Laparoscopic Nissen Fundoplication: Analysis of 162 Patients

Sari

Gönüllü

Tiryaki

et al. 2016

International Surgery

View full text Add to dashboard Cite

We aimed to evaluate the frequency of the need for proton pump inhibitor treatment following laparoscopic Nissen fundoplication (LNF) for gastroesophageal reflux disease (GERD). A total of 162 patients with GERD were treated surgically with LNF from October 2006 to March 2010 in our surgery department. Diagnoses were made by using upper gastrointestinal system (GIS) endoscopy and 24-hour pH monitoring, and all the patients underwent routine LNF surgery. The patients were questioned regarding complaints and proton pump inhibitor (PPI) usage during the postoperative period, and 40 patients who had postoperative GIS symptoms were included. Upper GIS endoscopy with antral biopsy for Helicobacter pylori (HP) identification and multichannel intraluminal impedance pH (MII-pH) monitoring were applied, and all the data were evaluated. The median postoperative follow-up time was 1.84 6 0.850 (0.29-3.48) years. PPI treatment frequency was 37.5% (15 patients) in the 40 symptomatic patients, or 9.26% in all 162 patients who were operated on. The reason for PPI usage in 3 patients (7.5%) was regarded as recurrence. HP positivity was 67.5% in the symptomatic patients and 73.3% in the PPI treated group; 40% (6 patients) recovery was achieved in the HP (þ) patients by using an HP eradication treatment protocol. The operated patients displayed statistically significant results in increased quality of life (P ¼ 0.001) and lowered DeMeester scores (P ¼ 0.000) during the postoperative period when compared with the

show abstract

Section: Resultsmentioning

confidence: 77%

Section: Discussionmentioning

confidence: 99%

Laparoscopic Nissen Fundoplication: Analysis of 162 Patients

Sari

Gönüllü

Tiryaki

et al. 2016

International Surgery

View full text Add to dashboard Cite

show abstract

“…Studies have shown that laparoscopic fundoplication has multiple benefits over the traditional open approach, including improved cosmesis, reduced morbidity, decreased hospital stay, decreased respiratory complications, and faster recovery (1)(2)(3). The long-term outcomes of laparoscopic fundoplication are comparable to open surgery in subjective symptoms.…”

Section: Introductionmentioning

confidence: 67%

Development of a novel ex vivo porcine laparoscopic Heller myotomy and Nissen fundoplication training model (Toronto lap-Nissen simulator)

Ujiie

Kato

et al. 2017

J. Thorac. Dis.

View full text Add to dashboard Cite

Background: Surgical trainees are required to develop competency in a variety of laparoscopic operations.Developing laparoscopic technical skills can be difficult as there has been a decrease in the number of procedures performed. This study aims to develop an inexpensive and anatomically relevant model for training in laparoscopic foregut procedures.Methods: An ex vivo, anatomic model of the human upper abdomen was developed using intact porcine esophagus, stomach, diaphragm and spleen. The Toronto lap-Nissen simulator was contained in a laparoscopic box-trainer and included an arch system to simulate the normal radial shape and tension of the diaphragm. We integrated the use of this training model as a part of our laparoscopic skills laboratorytraining curriculum. Afterwards, we surveyed trainees to evaluate the observed benefit of the learning session.Results: Twenty-five trainees and five faculty members completed a survey regarding the use of this model. Among the trainees, only 4 (16%) had experience with laparoscopic Heller myotomy and Nissen fundoplication. They reported that practicing with the model was a valuable use of their limited time, repeating the exercise would be of additional benefit, and that the exercise improved their ability to perform or assist in an actual case in the operating room. Significant improvements were found in the following subjective measures comparing pre-vs. post-training: (I) knowledge level (5.6 vs. 8.0, P<0.001); (II) comfort level in assisting (6.3 vs. 7.6, P<0.001); and (III) comfort level in performing as the primary surgeon (4.9 vs.7.1, P<0.001). The trainees and faculty members agreed that this model was of adequate fidelity and was a representative simulation of actual human anatomy. Conclusions:We developed an easily reproducible training model for laparoscopic procedures. This simulator reproduces human anatomy and increases the trainees' comfort level in performing and assisting with myotomy and fundoplication.

show abstract

“…Laparoskopik ameliyatların popüler olmasından sonra cerrahi endikasyonlar tekrar gözden geçirilmiş ve tedavi algoritmasındaki yeri yeniden önem kazanmıştır. Laparoskopik yöntemlerin gelişmesi ve yaygınlaşması ile cerrahi tedavinin morbidite, mortalite ve nüks oranlarında düşme görülmüştür [3]. Laparoskopik antireflü cerrahi yapılan hastaların uzun dönem takibinde, hastaların çoğun-da mükemmel sonuçların elde edildiği görülmüştür [4,5].…”

Section: Introductionunclassified

Laparoscopic Nissen Fundoplication, Single Center Experience

Karaca¹

2015

Ann Clin Anal Med

View full text Add to dashboard Cite

ÖzetAmaç: Gastroözofageal reflü hastalığının tedavisi için uyguladığımız Laparoskopik Nissen Fundoplikasyonu ameliyatlarının sonuçlarını değerlendirmek. Gereç ve Yöntem: Kliniğimizde Ocak 2008 ile Temmuz 2012 tarihleri arasın-da Laparoskopik Nissen Fundoplikasyonu uygulanan 81 hasta, geriye dönük olarak incelendi. Hastalardan 45'i kadın (%56), 36'si erkekti (%44). Ortalama yaş 40'tı (20-67). Hastaların tamamına ameliyat öncesinde en az 2 ay süre ile medikal tedavi verildi. Tüm hastalara ameliyat öncesi endoskopi ve özo-fagus biyopsisi yapıldı. Ameliyatlar genel anestezi altında 5 port kullanılarak yapıldı. Bulgular: Hastaların tamamında göğüste yanma ve mide içeriğinin ağza geri gelmesi şikâyetleri mevcuttu. Şikâyetlerin başlamasından ameliyata kadar geçen süre ortalama 12 aydı (4 ay-8 yıl). Ameliyat öncesi endoskopik incelemede bütün hastalarda özofajit tespit edildi. Histopatolojik incelemede, 6 hastada Barrett özofajiti saptandı. Ortalama ameliyat süresi 68 dakika (45-120 dk), ortanca hastanede kalış süresi 3 gün (1-7 gün) idi. Ortanca takip süresi 13 ay olarak belirlendi (7-40 ay). Bir hasta ilk ameliyatından 10 ay sonra nüks hiyatus fıtığı nedeniyle tekrar ameliyat edildi. Fonksiyonel sonuçlar hastaların %76'sında mükemmel, %14'ünde iyi, %10'unda orta olarak değerlendirildi. Tartışma: Laparoskopik Nissen Fundoplikasyonu, gastroözo-fageal reflü hastalığının tedavisinde, düşük morbidite ve mortalite oranı ile uygulanabilecek ve uzun süreli ilaç tedavisine alternatif, cerrahi bir girişimdir. Anahtar KelimelerNissen Fundoplikasyonu; Gastroözofageal Reflü Hastalığı Abstract Aim: Evaluate the outcomes of laparoscopic Nissen fundoplication surgery for the treatment of gastroesophageal reflux disease. Material and Method: Examined in our clinic, between January 2008 and July 2012 of 81 patients laparoscopic Nissen fundoplication administered retrospectively. 45 patients were female (56%) and 36 men (44%). Average age was 40 (20-67). Medical treatment was given to all patients for at least 2 months before the surgery. Endoscopy and esophageal biopsy was performed in all patients preoperatively. Operations were performed under general anesthesia, using 5 ports. Results: All patients, there were heartburn and stomach contents come into the mouth. The average time between the start of complaints surgery 12 months (range, 4 months-8 years). Endoscopic examination was detected esophagitis in all patients preoperatively. Barrett's esophagitis was found in 6 patients, histopathologic examination. Mean operative time was 68 min (45-120 min), and the median length of hospital stay 3 days (1-7 days). The median follow-up time was determined as 13 months (7-40 months). One patient was re-operated hiatus hernia recurrence of 10 months after the first surgery. The functional results were excellent in 76% of patients, 14% good, 10% as medium. Discussion: Laparoscopic Nissen fundoplication is a surgical initiative, the treatment of gastroesophageal reflux disease, with low morbidity and mortality rates can be applied, and an alter...

show abstract

Randomized clinical trial of laparoscopic versus open fundoplication: blind evaluation of recovery and discharge period

Abstract: Laparoscopic fundoplication was associated with a longer operating time, better respiratory function, less need for analgesics and a shorter hospital stay, while no reduction in the duration of postoperative sick leave was found compared with open surgery.

Cited by 131 publications

References 14 publications

Laparoscopic Nissen Fundoplication: Analysis of 162 Patients

Laparoscopic Nissen Fundoplication: Analysis of 162 Patients

Development of a novel ex vivo porcine laparoscopic Heller myotomy and Nissen fundoplication training model (Toronto lap-Nissen simulator)

Laparoscopic Nissen Fundoplication, Single Center Experience

Contact Info

Product

Resources

About