Randomized comparison of long-term desmopressin and alarm treatment for bedwetting

Evans, Jonathan; Malmsten, Birgitta; Maddocks, Alison; Popli, Harbans Singh; Lottmann, Henri

doi:10.1016/j.jpurol.2010.04.018

Cited by 34 publications

(53 citation statements)

References 31 publications

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“…In our series, 54.8% of 42 families which we established full contact, compliance with the EAD use appeared to be 54.8 percent. Our study results resembles to those of the study performed by Evans et al [11] which indicated patient's preference as the most important reason for early termination of the alarm therapy. Underlying causes of this phenomenon were as follows: cables, and pads of the device which complicate adherence to alarm therapy, repeated episodes of awakenings, and lack of active involvement of the parents in the treatment processş Another striking data of this study is the impact of EAD on the sleep duration.…”

Section: Discussionsupporting

confidence: 91%

“…Frequent washings, and home dependency during during night hours trigger development of emotional stress in parents. [8] Tolerability levels of especially working parents decrease in parallel with poorer sleep quality. A 35% of the families with enuretic children believe that their children should be punished for bedwetting.…”

Section: Discussionmentioning

confidence: 99%

“…Since minimal duration of therapy is at least 6-8 weeks, families'compliance to treatment decreases with time. [10] Evans et al [11] prospectively evaluated data of 251 patients from 29 clinics, and compared desmopressin with EAD. This study analyzed data gathered from centers in England, France, and Denmark, and adherence to EAD was defined as usage of the device longer than 75% of the treatment period.…”

Section: Discussionmentioning

confidence: 99%

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Family compliance with the use of alarm devices in the treatment of monosymptomatic nocturnal enuresis

Oğuz¹,

Sarıkaya²,

Özyuvalı³

et al. 2014

Turkish Journal of Urology

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Objective: In the treatment of monosymptomatic nocturnal enuresis (MNE), enuretic alarm devices (EADs) are the first recommended treatment option. This study aimed to evaluate parental and child compliance with EAD treatment. Material and methods:Fifty patients for whom EAD therapy was recommended were included in this study. The mean age of the patients was 10.4 years (5-16). All the patients were nursery or school children. Patients who did not return for their follow-up visits were called by phone, and verbal information were gathered about the use and performance success of the device. We documented the patients who used, and did not use the EAD with their reasons.Results: Nineteen (36%) patients were able to use the EAD without any problems. Eight of the remaining 31 patients didn't return for control, and they could not be get in touch with, either. Of the 23 (46%) families whom we could get a contact, 4 families did not purchase EAD due to a decrease in the number of wet nights, 4 families due to compensatory payment,and 3 families due to reluctance of one of the parents. One family reported that they gave up the EAD treatment because of the disturbing loud volume of the device. Four families reported that their children refused to use the EAD. Four families said that they could not use the EAD regularly because the device frequently did not work properly. In this study, we could not keep in touch with 16% of the patients, and 46% of the patients stopped using or did not receive this therapy. Conclusion:Although EAD has been the priorly recommended alternative with its relatively higher success, and lower recurrence rates, our study demonstrated that the compliance of families with this treatment is below the expected level.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Family compliance with the use of alarm devices in the treatment of monosymptomatic nocturnal enuresis

Oğuz¹,

Sarıkaya²,

Özyuvalı³

et al. 2014

Turkish Journal of Urology

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“…In addition, this condition is also related with the negative quality of life of their mothers [17]. Emotional stress in parents can be seen because of frequent washings, and home dependency during night times [18]. So the treatment is also associated with the quality of life of both parents as well as children.…”

Section: Discussionmentioning

confidence: 99%

The Time of Spontaneous Resolution of Monosymptomatic Nocturnal Enuresis (MNE) Is Familial

Oğuz¹,

Aykaç²,

Demirelli³

et al. 2015

Urol Int

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Purpose: To investigate whether or not the age of spontaneous resolution of monosymptomatic nocturnal enuresis (MNE) was familial. Patients and Methods: A questionnaire was administered to more than 1,500 people, and 100 appropriate participants were identified from four referral hospitals. We included the participants who had MNE and whose parents also had MNE with spontaneous resolution. Then the association between the spontaneous resolution time of MNE in parents and that in their children was investigated. Results: The mean ages of spontaneous resolution were 10.7 (10-30 years), 9.4 (6-17 years) and 10.9 (6-18 years) in participants, their mothers and their fathers, respectively. According to the statistical analysis, there was a positive correlation between participants and both their mothers and fathers (p < 0.05). In addition, it was revealed that familial MNE history based on first- and second-degree relatives, in addition to their parents, was also associated with the increased spontaneous resolution age of MNE (p < 0.05). According to our results, gender and parents' education status were not statistically associated with the spontaneous resolution (p > 0.05). Conclusion: As a conclusion, the age of spontaneous resolution of MNE is familial. Although the exact reasons of spontaneous resolution still remain a mystery; further genetic investigations may be able to resolve this mystery.

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“…All those factors may be the cause of the relapses in the present study. In a research study by Evans (2011) it was found that it would give the possibility of a family disruption since it was clearly shown that the withdrawal from the alarm group was high, indicating the importance of considering family motivation before selecting treatment, for optimal outcome. When considering the use of alarms, the child involved, as well as the parents/carers, should be informed that it may take a few weeks before the alarm starts to have an effect, and it may take weeks before dry nights are achieved and also if bedwetting restarts after stopping treatment, use of the alarm can be restarted without consulting a health professional as there is always a risk of that condition in long term period.…”

Section: Discussionmentioning

confidence: 99%

A Two Years Follow-Up Study of Children with Monosymptomatic Enuresis Treated with Enuresis Alarm

Özgür¹,

Ekıcı²,

Karakan³

et al. 2013

PRIJ

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Objective: Nocturnal enuresis is a common problem among children. This multifactorial disease is a source of stress of the families. Therefore, it is important how to approach the disorder, plan the treatment in order to provide a satisfactory cure rate. The aim of this study was to evaluate the long term results of alarm therapy after an initial response. Materials Methods:The study consisted of 36 of 50 patients with nocturnal enuresis, that were responded alarm therapy after three months treatment. At the end of the second year, detailed interviews with the parents of the children were recorded.Results: It was found that only 6 (16.7%) patients achieved complete dryness with the alarm device and no different treatment modalities were needed after the initial success. The remaining 30 (83.3%) patients had recurrence in the subsequent period and 25 (%83.3) of them tried retreatment. Conclusions:In long term follow up recurrence rates are high and families may seek different treatment approaches. Recurrence probabilities should be emphasized to the families at the beginning of the alarm treatment for monosymptomatic nocturnal enuresis.

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Randomized comparison of long-term desmopressin and alarm treatment for bedwetting

Cited by 34 publications

References 31 publications

Family compliance with the use of alarm devices in the treatment of monosymptomatic nocturnal enuresis

Family compliance with the use of alarm devices in the treatment of monosymptomatic nocturnal enuresis

The Time of Spontaneous Resolution of Monosymptomatic Nocturnal Enuresis (MNE) Is Familial

A Two Years Follow-Up Study of Children with Monosymptomatic Enuresis Treated with Enuresis Alarm

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