Randomized controlled trial of thermal balloon ablation versus vaginal hysterectomy for leiomyoma-induced heavy menstrual bleeding

Abstract

TBA can replace vaginal hysterectomy in some perimenopausal women with uterine leiomyomas. Clinical Trials Registry India: CTRI/2016/07/007119.

Bipolar Endometrial Resection (BER) Versus Non Descent Vaginal Hysterectomy (NDVH) For Leiomyoma Induced Heavy Menstrual Bleeding

“…The present trial assessed other leiomyomata induced symptoms after BER and NDVH, improvements of symptoms were found to reach significant level in both groups, including dysmenorrhea, backache, pelvic pain, dyspareunia. This results like that of Jain et al (15) and this could be explained by decrease of prostaglandins synthesis by removed endometrium.…”

Choice of primary and secondary outcomes in randomised controlled trials evaluating treatment for uterine fibroids: a systematic review

“…Other QoL measures included the Short-Form 36 questionnaire (six RCTs), the EuroQol 5D questionnaire (four RCTs), a non-specified scale (two RCTs), the Health Utilities Mark 3 questionnaire (one RCT), the Urogenital Distress Inventory (one RCT), the Incontinence Impact Questionnaire (one RCT), the Defecation Distress Inventory (one RCT), the EuroQol Visual Analogue Scale (one RCT), the World Health Organization Quality of Life BREF Questionnaire (one RCT), patient report (one RCT), relief of symptoms on a ten-point scale (one RCT) and a five-point questionnaire (one RCT). 20,25,27,33,44,56,67,71,73,74,76,78,86,91 The median number of participants per study was 80 (IQR 70, minimum 16, maximum 384) (Table S4). The majority of trials were published in an obstetrics and gynaecology journal (34 out of 60 studies, 56.7%) with the remainder being published in specialist radiology journals (15 out of 60 studies, 25%) and general medical or surgical journals (11 out of 60 studies, 18.3%).…”

“…The validated Uterine Fibroid Symptom and QoL Questionnaire was used as a measure in nine trials. Other QoL measures included the Short‐Form 36 questionnaire (six RCTs), the EuroQol 5D questionnaire (four RCTs), a non‐specified scale (two RCTs), the Health Utilities Mark 3 questionnaire (one RCT), the Urogenital Distress Inventory (one RCT), the Incontinence Impact Questionnaire (one RCT), the Defecation Distress Inventory (one RCT), the EuroQol Visual Analogue Scale (one RCT), the World Health Organization Quality of Life BREF Questionnaire (one RCT), patient report (one RCT), relief of symptoms on a ten‐point scale (one RCT) and a five‐point questionnaire (one RCT) 20,25,27,33,44,56,67,71,73,74,76,78,86,91 …”

Abnormal uterine bleeding: hysterectomy versus resection

“…Regarding pain in the postoperative period, data from controlled studies vary; two controlled studies reported no significant differences in the 24-month period under review 6,7 . Two controlled studies state that pain was higher in patients undergoing hysterectomy than in those undergoing endometrial ablation 11,12 . A randomized study that focused its analysis on the reoperation rate and quality of life did not analyze pain 13 .…”