Randomized controlled trial on lateral augmentation using two collagen membranes: morphometric results on mineralized tissue compound

Abstract

Conflict of interest and source of funding statementThe authors declare that they have no conflict of interest. The study was funded in parts by

Tissue reactions after simultaneous alveolar ridge augmentation with biphasic calcium phosphate and implant insertion—histological and immunohistochemical evaluation in humans

“…As indicated in Table 2, 13 biopsies selected from a total of 38 sites enrolled into the previous study were finally available [12], as most specimens included in the pilot study were classified as inappropriate for the present analysis due to the minimal size of tissues retrieved in some cases. Furthermore, a subgroup of patients included in the pilot study exhibited compromised wound healing, which resulted in premature exposure of bone substitute material to the oral environment.…”

“…The harvesting procedure of newly mineralized augmented tissues as much as the amount of tissue obtained was non-standardized, as an equal approach to each surgical site was impossible. The specimens processed for histology in this investigation represent a part of a total patient cohort participating in a former clinical study [12]. For this investigation, only biopsies providing enough material for adequate and valid histological analysis were integrated into the sample collective; for which reason, this study comprises a smaller sample size than the preceding one.…”

“…Clinical procedures and biopsy recruitment have been conducted as previously described [12,13]. In brief, simultaneous augmentation and implant surgery was carried out under local anesthesia (Ultracain DS forte, Aventis, Germany) by a single surgeon (A.F.).…”

“…90 % and pores with 100-500 μm in diameter. Morphometrical analyses of BCP performance in a simultaneous grafting approach revealed statistically significant differences in the amount of newly formed mineralized tissues after 6 months in situ when comparing a native non-crosslinked collagen membrane (NCCM) with a ribose crosslinked collagen membrane (RCCM) [12]. In both membrane groups, the healing was compromised in approximately 50 % of the cases although all sites were carefully closed upon augmentation surgery by tensionless adaption of the soft tissue flap.…”

Effect of cross‐linked vs non‐cross‐linked collagen membranes on bone: A systematic review

“…All the authors specified the brand of the dental implants used when bone regeneration was required except for Tal et al . From which, Camlog ® (Basel, Switzerland) was the most frequently used with a percentage of 40.27%, followed by Straumann ® (Basel, Switzerland) with 15.14% . Moses et al .…”