Randomized controlled trials evaluating laparoscopic vs. open distal gastrectomy for gastric cancer in 2016: a trilogy finally!

Kim, Young Woo; Yang, Hannah

doi:10.21037/tgh.2017.03.06

Cited by 1 publication

(2 citation statements)

References 19 publications

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“…However, it is similar to the time taken in the open subgroup of the study by Inokuchi et al 33 The average blood loss in LG is significantly lower than in open surgery. 32,33,37 The average blood loss of 104 ± 50 mL in our series is comparable to other reports of laparoscopy in AGC. 33 Major (≥ CD class 3) complications post-gastrectomy have been reported to be around as low as 1.2% 31 in early lesions and can be seen up to 15% 33 in locally advanced cases.…”

Section: Discussionsupporting

confidence: 84%

“…Most of the studies on LG published so far have argued that surgeon's experience has a defining role in outcomes of surgery. 32 It is one of the technically demanding procedures and an average of 50 surgeries is required to achieve optimal proficiency. 43,[45][46][47] In a study by Kim et al postoperative local complications (1.608 times greater than ODG), reoperation rates (3.008 times greater than ODG) as well as operative time were influenced independently by a lack in surgical experience.…”

Section: Discussionmentioning

confidence: 99%

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Laparoscopic D2 gastrectomy in advanced gastric cancer: Postoperative outcomes and long‐term survival analysis

Chittawadagi

Nayak

Parthasarathi

et al. 2021

Asian J Endoscop Surgery

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Introduction: Data on laparoscopic treatment of operable gastric cancer from India is sparse. This study aims to document outcomes of laparoscopic D2 gastrectomy in an Indian population.Materials and methods: Data of patients who underwent laparoscopic D2 gastrectomy for operable advanced gastric cancer between February 2012 and January 2017 were collected from electronic hospital records supplemented by telephonic interviews and analyzed. Survival was evaluated using Kaplan-Meier survival analysis curves.Results: In total 121 patients were included. Conversion to open gastrectomy was 5.7%. One hundred and fourteen patients (73 laparoscopic subtotal gastrectomy and 41 laparoscopic total gastrectomy) were included for analysis. D2 lymphadenectomy was done in all cases; mean number of dissected lymph nodes was 23.12 ± 9.14 (12-45). Major complications (Clavien-Dindo Grade III and IV) was seen in 6.1% of cases with reoperation rate of 3.5% (4/114). Stage 3 disease was seen in 60.6% cases and stage 2 disease in 32.5%. Follow-up data were available for 76.3% of patients with mean follow-up of 29.5 months. Overall survival across all stages was 38.7 months. Five-year disease-free survival and overall survival were 36.7% and 55.9% respectively, across all stages. Conclusion:Laparoscopic D2 gastrectomy is safe, feasible with similar postoperative complications and comparable survival outcomes across all stages when compared to available literature on open gastrectomy cases.

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