Randomized, Placebo-Controlled Trial of Chinese Herb Therapy for HIV-1–Infected Individuals

Weber, Rainer; Christen, Lisanne; Loy, Monika; Schaller, Silvio; Christen, Stephan; Joyce, C.R.B.; Ledermann, Ueli; Ledergerber, Bruno; Cone, Richard W.; Lüthy, Ruedi; Cohen, Misha

doi:10.1097/00042560-199909010-00007

Cited by 33 publications

(19 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Among other aspects the author of the latter study [20] related the results of the study to the fact that the standardized TCM therapy is not effective in a 'Western setting'. A further factor influencing the external validity of the studies is the taking into account of proper diagnostics in the sense of TCM as a crucial condition for the choice of the adequate therapy and its success.…”

Section: Discussionmentioning

confidence: 99%

“…The languages used in the publications were Chinese (23) and English (20). Of the 33 controlled trials 24 were randomized.…”

Section: Study Design and Study Realizationmentioning

confidence: 99%

“…25 articles provided no data on this aspect. Of the 7 studies with 'adequate' documentation the results are distributed as follows: 2 studies stated that the therapy was well tolerated and that no side effects had occurred [14,15]; 2 studies report 'no difference' between the groups [16,17] while 3 studies mention [18][19][20] e.g. gastrointestinal symptoms, xerostomia and micturation problems as side effects.…”

Section: Population and Indicationmentioning

confidence: 99%

“…7 studies were excluded as no information was provided about the diagnostic process or no statistical evaluation had been carried out. Of the 4 randomized double-blind studies for which the internal validity was graded 'adequate' 3 were found to have a significantly positive result for the TCM group [18,21,22] while 1 study showed no difference between the therapy groups [20]. The 4 trials which evaluated traditional individual TCM therapy (only 3 provide statistical analysis) yielded a 'significantly positive result for the TCM treated group' [21,23,24].…”

Section: Population and Indicationmentioning

confidence: 99%

See 3 more Smart Citations

Traditional Chinese Medicine (Phytotherapy): Health Technology Assessment Report – Selected Aspects

Maxion-Bergemann¹,

Bornhöft

Sonderegger

et al. 2006

Forsch Komplementärmed

View full text Add to dashboard Cite

Objective: A summary of main aspects from a Health Technology Assessment report on Traditional Chinese Medicine (TCM) in Switzerland concerning effectiveness and safety is given. Materials and Methods: Literature search was performed through 13 databases, by scanning reference lists of articles and by contacting experts. Assessed were quality of documentation, internal and external validity. Results: Effectiveness: 43 articles concerning ‘gastrointestinal tract and liver’ were assessed. The studies covering 7,436 patients were undertaken in China (35), Japan (3), USA (2) and Australia (3); 33/43 being controlled studies. 34/40 show significantly better results in the TCM-treated group. A comparison of studies on results of treatment based on a diagnosis according to TCM criteria and studies on results of treatment according to Western diagnosis shows that treatment based on TCM diagnosis improves the result. The comparison of treatment by individual medication and standard medication showed a trend in favor of individual medication. Safety: TCM training and practice for physicians in Switzerland are officially regulated. Side effects occur, but no severe effects have been registered up to now in Switzerland. TCM medicinals are imported; admission regulations are being installed. Problems due to production abroad, Internet trade, self-medication or admixtures are possible. Conclusion: The evaluation of the literature search provides evidence for a basic clinical effectiveness of TCM therapy. Severe side effects were not observed in Switzerland. Regulations for trading and use of medicinals prevent treatment risks. Further clinical studies in a Western context are required.

show abstract

Section: Discussionmentioning

confidence: 99%

“…The languages used in the publications were Chinese (23) and English (20). Of the 33 controlled trials 24 were randomized.…”

Section: Study Design and Study Realizationmentioning

confidence: 99%

Section: Population and Indicationmentioning

confidence: 99%

Section: Population and Indicationmentioning

confidence: 99%

See 2 more Smart Citations

Traditional Chinese Medicine (Phytotherapy): Health Technology Assessment Report – Selected Aspects

Maxion-Bergemann¹,

Bornhöft

Sonderegger

et al. 2006

Forsch Komplementärmed

View full text Add to dashboard Cite

show abstract

“…Their study also cross-validated improvement in quality of life by patients' global evaluation and practitioners' objective assessments. HRQOL assessment of the effectiveness and efficacy of TCM have also been applied to studies on HIV [121] , hepatitis C virus [122,123], vomiting and nausea in pregnant women [124], chronic alcoholism [125] and somatoform disorders [126].…”

Section: Applications Of Hrqol Measures In Tcm Treatments Of Other Comentioning

confidence: 99%