Randomized, Prospective, Comparative Trial of EX-PRESS Glaucoma Filtration Device versus Trabeculectomy (XVT Study)

Use of Various Glaucoma Surgeries and Procedures in Medicare Beneficiaries from 1994 to 2012

“…Nonetheless, when the combined volume of conventional trabeculectomies and external minishunts was assessed, a more modest 9% decrease in use was observed between 2009 and 2012, suggesting that Ex-PRESS shunt implantation is possibly being substituted for conventional trabeculectomies in both surgically naive eyes and those with prior surgery. A prospective, randomized study did not demonstrate an advantage of ExPRESS shunt implantation over conventional trabeculectomy, 17 although some smaller retrospective studies have suggested fewer postoperative complications and more rapid visual recovery with similar surgical success rates. 18e30 Procedures other than external mini-shunt implantation also may be contributing to the procedural decline in conventional trabeculectomy.…”

Comparison of trabeculectomy versus Ex-PRESS: 3-year follow-up

“…Dahan et al 8 randomised fellow eyes of 15 patients and after a mean follow-up of 23.6 months reported better success rates with the Ex-PRESS implant, although there was no difference in mean intraocular pressure (IOP). The other two studies found no difference in success rates between Ex-PRESS and trabeculectomy, with follow-up periods of 1 and 2 years, respectively 2 6…”

Early Clinical Results of a Novel Ab Interno Gel Stent for the Surgical Treatment of Open-angle Glaucoma

“…Studies support a lower complication rate with the device compared with traditional trabeculectomy although the technique still requires surgical incision of the conjunctiva and presence of a scleral flap. [8][9][10] The flow of aqueous is ultimately regulated in a similar manner to trabeculectomy through varying techniques of flap creation and flap suture tension and postoperative suture manipulation.…”