Introduction
Black men are diagnosed with prostate cancer (PCa) at nearly twice
the rate of white men and are underrepresented in PCa research, including
validation studies of new clinical tools (e.g., genomic testing). Since
healthcare system mistrust has contributed to these disparities for
centuries, black men may be less inclined to pursue novel testing and
facilitators of their PCa research study participation remains
warranted.
Methods
A community-engaged approach involving a partnership with a community
organization was utilized to conduct 7 focus groups in Minnesota, Alabama,
and California to explore black men’s attitudes toward PCa research
participation and genomic testing for PCa. Data were collected and analyzed
from April 2015-April 2017.
Results
Identified genomic testing barriers included a lack of terminology
understanding, healthcare system mistrust, reluctance to seek medical care,
and unfavorable attitudes toward research. Facilitators included family
history, value of prevention, and the desire for health education. Lack of
PCa knowledge, PSA testing confusion, health care system distrust, and
misuse of personal health information were barriers to research study
participation. Some black men were motivated to participate in research if
seen as constructive and transparent.
Conclusions
Disparities for black men can both motivate and disincentivize
participation depending upon a positive or negative view of research.
Confusion over PCa clinical care has fueled some mistrust among black men
affecting both clinical care and research participation. With increased
education, health literacy, and assurances of research integrity and
transparency, black men may be more willing to participate in PCa testing
and research.