Range of Accuracy of Two Wavelength Oximetry

Chapman, Kenneth R.; Liu, F.L.W.; Watson, Rebecca B.; As, Rebuck

doi:10.1378/chest.89.4.540

Cited by 54 publications

(10 citation statements)

References 6 publications

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“…With the marked improvement in instrumentation, this technique, which is based on transmission of light through the vascular bed of the ear lobe ( 5 ) , is now gaining increasing attention, both for research and clinical purposes (2,3,4).…”

Section: Introductionmentioning

confidence: 99%

Ear Oximetry during Progressive Hypoxia

Gíslason

Sandhagen

Daskalopouloul

1988

Upsala Journal of Medical Sciences

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The BIOX I11 Pulse oximeter for measuring arterial oxygen saturation (Sa02) was compared during rest and under progressively hypoxic conditions, with Sa02 values based on arterial blood samples. The measurements were performed in 16 subjects undergoing tests of ventilatory response to hypoxia, by a rebreathing method.For each individual subject, there was a linear response relationship (r=0.99), while for all 126 comparative values the regression equation was: y= 0.83 X + 14.7 (r=0.98). The observed ventilatory response was lower when the calculations were based on oximeter readings. We conclude that the oximeter has acceptable correlation between the BIOX I11 and Sa02 measurements for clinical use, especially when Sa02 is above 70%.

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Section: Introductionmentioning

confidence: 99%

Ear Oximetry during Progressive Hypoxia

Gíslason

Sandhagen

Daskalopouloul

1988

Upsala Journal of Medical Sciences

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“…The patient described in this present report had marked reductions in oxyhemoglobin levels when determined using the pulse oximeter, and these were much lower than would be predicted from the co-oximetry readings shown in Table I. Furthermore, shifts of the oxyhemoglobin dissociation curve alone should not alter the pulseoximeter-determined oxyhemoglobin levels unless a hemoglobin variant with different spectral properties at 660 and 940 nm is also present [3][4][5][6][7]. That we find hemoglobin Cheverly to also result in an artifactually low pulse-oximeter oxyhemoglobin level as did hemoglobins Köln [9,10] and Hammersmith [11], raises the possibility that this pulse oximetry abnormality is a general property of unstable hemoglobins.…”

Section: Discussionmentioning

confidence: 94%

“…Pulse oximetry is an accepted noninvasive method that enables continuous measurement of hemoglobin oxygen saturation [1][2][3]. The ability of this technique to accurately measure hemoglobin oxygen saturation is dependent upon both instrumental and biological considerations [1][2][3][4][5][6]. Because these instruments estimate hemoglobin oxygen saturation by measuring light absorption of perfused tissue at 660 and 940 nm during arterial pulses, there are theoretical concerns that differences of hemoglobin absorptive spectra may result in significant misleading estimates in estimated hemoglobin oxygen saturations.…”

Section: Introductionmentioning

confidence: 99%

Low pulse oximeter‐measured hemoglobin oxygen saturations with hemoglobin Cheverly

Hohl

Sherburne

Feeley³

et al. 1998

Am. J. Hematol.

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Unexpectedly low hemoglobin oxygen saturation as determined by pulse-oximeter analysis was observed in a patient who underwent an elective surgical procedure. Specific hemoglobin derivatives such as carboxyhemoglobin, methemoglobin, and reduced hemoglobin that have been described to lower pulse-oximetry determination of oxygenation were not detected. Absorbance spectra revealed the patient's hemoglobin to be different than that obtained from two normal volunteers. High-pressure liquid chromatographic analysis of the hemoglobin showed an unknown band that comprised 15% of the patient's hemoglobin. DNA sequence analysis showed a point mutation in the second nucleotide of the 45th codon of the ␤-globin chain. This mutation encodes for an abnormal ␤-chain (␤-45 Phe→Ser) that has been described as hemoglobin Cheverly. Hemoglobin Cheverly is an unstable hemoglobin that has a similar mutation as the ␤-42 Phe→Ser mutation seen in hemoglobin Hammersmith. Hemoglobin Hammersmith and another unstable hemoglobin, hemoglobin Kö ln, have previously been described to have unexpectedly low pulse-oximeter-determined oxyhemoglobin levels. That we find hemoglobin Cheverly to result in a similar phenomenon suggests that pulse-oximeter monitoring of oxygenation status may not be appropriate for the unstable hemoglobins. Low pulseoximeter oxygenation determinations for these hemoglobins do not appear to predict clinical hypoxemia. Am.

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“…Arterial blood oxygenation is determined by direct measurement of arterial oxygen tension from arterial blood gases (ABG) or by non‐invasive measurement of oxygen saturation using pulse oximetry. Pulse oximetry has been established as a rapid and non‐invasive method of measuring arterial oxygenation with an accepted error of 2% at oxygen saturation of >75% (4). A pulse oximeter utilises the principles of spectrophotometry with those of photoelectric plethysmography.…”

Section: Definition Of Oxyhemoglobin Saturationmentioning

confidence: 99%

“…Arterial blood oxygenation is determined by direct measurement of arterial oxygen tension from arterial blood gases (ABG) or by non-invasive measurement of oxygen saturation using pulse oximetry. Pulse oximetry has been established as a rapid and non-invasive method of measuring arterial oxygenation with an accepted error of 2% at oxygen saturation of >75% (4). A pulse Abstract: Objective: To evaluate agreement among various methods for measuring oxyhemoglobin (O 2 Hb) saturation in adult hypoxic patients with sickle cell disease (SCD) during painful vaso-occlusive crisis and to compare those results with a control group.…”

mentioning

confidence: 99%