Nichols algebras are fundamental objects in the construction of quantized enveloping algebras and in the classification of pointed Hopf algebras by the lifting method of Andruskiewitsch and Schneider. The structure of Cartan graphs can be attached to any Nichols algebras of diagonal type and plays an important role in the classification of Nichols algebras of diagonal type with a finite root system. In this paper, the main properties of all simply connected Cartan graphs attached to rank 6 Nichols algebras of diagonal type are determined. As an application, we obtain a subclass of rank 6 finite dimensional Nichols algebras of diagonal type.