Office layout design is pertinent in terms of ergonomics to obtain a sustainable workspace. There are five workplace evaluation parameters to be considered, namely successiveness, work within the limits of biological ability, work within the limits of sustainable work performance, work within the social limits, and work fulfilling psychological expectations and individual satisfaction of being able to exercise all abilities. In ergonomics, job satisfaction is an essential matter for an employee to perform a task productively. Since the office design mostly affects the worker's performance and health at the same time, it is a requirement to create sustainable workplace. Multi-criteria decision-making methods are not only broadly used in different fields and disciplines, but are also considered to be an essential field in ergonomics. This paper aimed to propose a method in order to analyze and compare the office layout design with the methods of analytical hierarchy process, elimination and choice translating reality, and permutation method. The criteria in this paper are established in a hierarchical order by employing these methods. All in all, office alternatives are compared, and the overall results are examined.