1984
DOI: 10.1016/s0034-5288(18)31950-7
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Rapeseed induced liver haemorrhage, reticulolysis and biochemical changes in laying hens: the effects of feeding high and low glucosinolate meals

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Cited by 45 publications
(21 citation statements)
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“…Research has shown teratogenic effects of other GSHPs in murine models, most notably allyl ITC (AITC) from sinigrin, 1-cyano-2-hydroxy-3,4-epithiobutane (CETB) from progoitrin, and iberin from glucoiberin [53]. The common symptoms seen in livestock often attributed to the overconsumption of GS/GSHPs are: slowed growth [54], impaired movement and general disorientation [55], impaired fertility [56], and damage to the thyroid, gastro-intestinal tract, and/or liver [57,58]. Because of what has been seen in animals, caution must be taken when manipulating GS and GSHP profiles.…”
Section: Glucosinolate Hydrolysis Products and Their Chemopreventimentioning
confidence: 99%
“…Research has shown teratogenic effects of other GSHPs in murine models, most notably allyl ITC (AITC) from sinigrin, 1-cyano-2-hydroxy-3,4-epithiobutane (CETB) from progoitrin, and iberin from glucoiberin [53]. The common symptoms seen in livestock often attributed to the overconsumption of GS/GSHPs are: slowed growth [54], impaired movement and general disorientation [55], impaired fertility [56], and damage to the thyroid, gastro-intestinal tract, and/or liver [57,58]. Because of what has been seen in animals, caution must be taken when manipulating GS and GSHP profiles.…”
Section: Glucosinolate Hydrolysis Products and Their Chemopreventimentioning
confidence: 99%
“…Thyroid enlargement and fetal deaths have been described in experimental rodents. Thyroid hypertrophy has also been reported in poultry (Martland et al, 1984;Wight et al, 1987). Thyroid hypertrophy has also been reported in poultry (Martland et al, 1984;Wight et al, 1987).…”
Section: Toxic Effects Of Glucosinolatesmentioning
confidence: 84%
“…Glucosinolates are reported to interfere with liver function by inducing alterations of hepatic detoxification system (Williamson et al, 1996). The decreased growth and reduced egg production that have been reported in poultry could be associated with decreased feed intake (Woyengo et al, 2011;Martland et al, 1984;Wight et al, 1987). Allyl isothiocyanates can cause irritant damage to the gastrointestinal tract (Taljaard, 1993;Mason and Lucas, 1983;Woyengo et al, 2011).…”
Section: Toxic Effects Of Glucosinolatesmentioning
confidence: 99%
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“…However, histopathological examination can clearly differentiate these two hepatic diseases in that chicken leucocytozoonosis shows characteristic megaloschizonts and associated tissue reactions in various organs including the liver [1112,1415] . Moreover, fatty liver and FLHS lead to fatty vacuoles in hepatocytes, and FLHS additionally presents with reticulolysis and vein degenerative changes [14,17] .…”
Section: Introductionmentioning
confidence: 99%