Rapid analysis of tetracycline in honey by microwave plasma torch mass spectrometry with ablation samples

Jiang, Tao; Peng, Zhen; Xie, Mengping; Fang, Xiaowei; Hong, Yi; Huang, Zhengxu; Gao, Wei; Zhou, Zhen; Li, Lei; Zhu, Zhiqiang

doi:10.1039/c9ay01887e

Cited by 27 publications

(17 citation statements)

References 39 publications

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“…In an early work, Gray M. Hieftje et al built an MPT-TOF MS for the detection of halogenated hydrocarbons separated by a capillary gas chromatography [ 131 ]. After a long time, Ti-Qiang Zhang as well as Zhi-Qiang Zhu [ 22 , 23 , 132 ] studied the direct desorption/ionization approach of MPT on a linear ion trap (LTQ) mass spectrometer to analyze a series of small organic molecules, and they showed that MPT is a useful alternative ambient ion source. Zhi-Qiang Zhu’s group [ 24 , 25 , 26 , 133 , 134 , 135 , 136 ] has also completed a lot of work on the detection of trace metal in aqueous solutions by MPT source, coupled with a mass spectrometer (MPT-MS), reaching an in-depth understanding of the characteristics of MPT.…”

Section: Mass Spectrometrymentioning

confidence: 99%

“…After starting with a brief review on the hazards, migration, distribution and traditional analysis methods of PAHs which are widely used in recent years, including liquid chromatography, gas chromatography and surface enhanced Raman spectroscopy and so on, we mainly want to present the applications of the modern ambient mass spectrometry in the detection of PAHs; in addition, we present the far out novel results in our lab by using microwave plasma torch (MPT) mass spectrometry, which exhibited the versatility of MPT MS as a platform in the research of PAHs. MPT ion source is a novel ambient ion generator and has multiple advantages, for example, simple construction of the device and easy operation, low power dissipation, relative high sensitivity, and suitable for many types of samples including metal elements and organic samples [ 22 , 23 , 24 , 25 , 26 ].…”

Section: Introductionmentioning

confidence: 99%

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Contemporary Research Progress on the Detection of Polycyclic Aromatic Hydrocarbons

Zhang

Yuan

et al. 2022

IJERPH

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Polycyclic aromatic hydrocarbons (PAHs) are a class of the most common and widespread contaminants. The accumulation of PAHs has made a certain impact on the environment and is seriously threatening human health. Numerous general analytical methods suitable for PAHs were developed. With the development of economy, the environmental problems of PAHs in modern society are more extensive and prominent, and attract more attention from environmental scientists and analysts. Deeper understanding of the properties of PAHs depends on the advent of detection methods, which can also be more conducive to promoting the protection of the environment. Till now, more sensitive, more high-speed and more high-throughput analytical tools are being invented and have played important roles in the research of PAHs. In this short review article, we focused mainly on the contemporary analytical methods about PAHs. We started with a brief review on the hazards, migration, distribution and traditional analysis methods of PAHs in recent years, including liquid chromatography, gas chromatography, surface enhanced Raman spectroscopy and so on. We also presented the applications of the modern ambient mass spectrometry, especially microwave plasma torch mass spectrometry, in the detection of PAHs, as well as the far out novel results in our lab by using microwave plasma torch (MPT) mass spectrometry; for example, some new insights about Birch reduction, regular hydrogen addition and the robustness of molecular structure. These studies have demonstrated the versatility of MPT MS as a platform in the research of PAHs.

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Section: Mass Spectrometrymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Contemporary Research Progress on the Detection of Polycyclic Aromatic Hydrocarbons

Zhang

Yuan

et al. 2022

IJERPH

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“…In the last decade, the MPT has shown excellent performance as an atmospheric pressure ion source for the analysis of organic and metallic elements. 28,29 In this work, we combined MPT and corona discharge as dual sources to enhance ionization efficiency and applied it to the analysis of sterols in urban water systems using Orbitrap MS. Preliminary results show that the dual source can be directly used for sterol detection, and four target sterols were detected in water samples collected from different areas of Hangzhou city.…”

Section: Introductionmentioning

confidence: 99%

“…The microwave plasma torch (MPT) ion source was developed by Jilin University, China, in 1985 and has been used as an excitation light source in AES. In the last decade, the MPT has shown excellent performance as an atmospheric pressure ion source for the analysis of organic and metallic elements 28,29 …”

Section: Introductionmentioning

confidence: 99%

Dual ambient plasma source ionization mass spectrometry for the rapid detection of trace sterols in urban water

2022

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A direct analytical method based on dual ambient plasma ion source tandem mass spectrometry was used for the simultaneous determination of four sterols in the environment. This technology has very high sensitivity and the method detects the four sterols in methanol–water (1:3) solutions with limits of detection (LOD) and limits of quantification (LOQ) ranging from 1.2 ng/L to 6.9 ng/L and 7.6 ng/L to 10.0 ng/L, respectively. The method was also used to test water quality at three locations within the city and successfully detected all four sterols at very low concentrations. The dual plasma source tandem mass spectrometry technique is extremely simple, rapid, sensitive and highly efficient compared to other traditional methods, providing a useful screening tool for sterols in water.

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“…Much research has been done on various ionization techniques optimizing performance for specific analyses. , The flexibility afforded by changing many physical or chemical parameters while performing ambient ionization has given practitioners many options to tailor the ion source to maximize performance. Examples of ionization methods for the antibiotic detection in complex matrixes include the following: electrospray ionization (ESI) for milk samples, − nano-electrospray ionization (nESI) for infant formula, paper spray for biofluids, microwave plasma torch (MPT) for honey, and extractive electrospray ionization (EESI) for viscous cosmetic products, with sample preconcentration and cleanup methods, such as solid-phase microextraction (SPME), ,, solid-phase extraction (SPE), or simplified extraction often being necessary to compensate for the lack of chromatographic separation. Requiring minimal sample preparation and time, ambient ionization is most impactful when coupled to mass spectrometers that can be operated outside an analytical laboratory.…”

Section: Introductionmentioning

confidence: 99%

Novel Ion Trap Scan Modes to Develop Criteria for On-Site Detection of Sulfonamide Antibiotics

Szalwinski

Morato

et al. 2021

Anal. Chem.

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Advances in ambient ionization techniques have facilitated the direct analysis of complex mixtures without sample preparation. Significant attention has been given to innovating ionization methods so that multiple options are now available, allowing for ready selection of the best methods for particular analyte classes. These ambient techniques are commonly implemented on benchtop systems, but their potential application with miniature mass spectrometers for in situ measurements is even more powerful. These applications require that attention be paid to tailoring the mass spectrometric methodology for the on-site operation. In this study, combinations of scan modes are employed to efficiently determine what tandem mass spectrometry (MS/MS) operations are most useful for detecting sulfonamides using a miniature ion trap after ionization. First, mixtures of representative sulfonamide antibiotics were interrogated using a 2D MS/MS scan on a benchtop ion trap in order to determine which class-specific fragments (ionic or neutral) are shared between the sulfonamides and thus have diagnostic value. Then, three less-used combination scans were recorded: (i) a simultaneous precursor ion scan was used to detect both analytes and an internal standard in a single ion injection event to optimize quantitative performance; (ii) a simultaneous precursor/neutral loss scan was used to improve detection limits; and finally, (iii) the simultaneous precursor/neutral loss scan was implemented in a miniature mass spectrometer and representative sulfonamides were detected at concentrations as low as 100 ng/mL by nano-electrospray and 0.5 ng absolute by paper spray ionization, although improvements in the stability of the home-built instrumentation are needed to further optimize performance.

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Rapid analysis of tetracycline in honey by microwave plasma torch mass spectrometry with ablation samples

Abstract: A rapid and sensitive mass spectrometric analysis method with minimal or no prior sample pretreatment was developed for the direct detection of trace amounts of tetracycline in honey products using a microwave plasma torch combined with mass spectrometry.

Cited by 27 publications

References 39 publications

Contemporary Research Progress on the Detection of Polycyclic Aromatic Hydrocarbons

Contemporary Research Progress on the Detection of Polycyclic Aromatic Hydrocarbons

Dual ambient plasma source ionization mass spectrometry for the rapid detection of trace sterols in urban water

Novel Ion Trap Scan Modes to Develop Criteria for On-Site Detection of Sulfonamide Antibiotics

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