Rapid and easy method for simultaneous measurement of widespread 27 compounds in natural products and foods

Ölmez, Özge Tokul; Şahin, Bihter; Çakir, Cansel; Öztürk, Mehmet

doi:10.25135/jcm.38.20.03.1589

Cited by 10 publications

(5 citation statements)

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“…The phenolic component analysis of methanol extract (ECM) of the leaves of E. citriodora was carried out using a modified method of Tokul-Ölmez et al (2020). In this study, 41 substances (fumaric acid, gallic acid, protocatechic acid, theobromine, theophylline, catechin, 4-hydroxy benzoic acid, 6,7-dihydroxycoumarine, methyl-1,4-benzoquinone, vanillic acid, caffeic acid, vanillin, chlorogenic acid, p-coumaric acid, ferrulic acid, cynarin, coumarine, prophylgallate, rutin, trans-2-hydroxycinnamic acid, ellagic acid, myricetin, fisetin, quercetin, trans cinnamic acid, luteoline, kaempherol, apigenin, chrysin, 4-hydroxy resorcinol, 1,4-dichlorobenzene, pyrocatechol, 4-hydroxybenzaldehyde, epicatechin, 2,4-dihydroxybenzaldehyde, hesperedin, oleuropein, naringenin, hesperetin, genistein, curcumin) were investigated in ECM extract using a Shimadzu high-performance liquid chromatography (Shimadzu Cooperation, Japan) system that consists of a Shimadzu model LC-20AT.…”

Section: Hplc-dad Analysismentioning

confidence: 99%

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Chemical composition and biological activities of essential oils and extract of Eucalyptus citriodora Hook

Şahin,

Cakır,

Sıcak

et al. 2024

International Journal of Secondary Metabolite

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In this study, the leaves of Eucalyptus citriodora Hook (Lemon-Scented Eucalyptus) were harvested and collected from Üzümlü neighborhood of Fethiye district of Muğla in 2021. Chemical content analysis of steam distillation and hydrodistillation of essential oils were determined by GC-MS, while phenolic content of methanol extract was determined by HPLC-DAD. Antioxidant activities of essential oils and methanol extracts were determined by DPPH radical removal, ABTS cation removal, β-carotene linoleic acid, and CUPRAC activity methods; Anticholinesterase activity against AChE and BChE enzymes was determined by Ellman method; and tyrosinase inhibition associated with melanin hyperpigmentation, α-amylase inhibition, and α-glucosidase inhibition activities associated with diabetes were determined as an in vitro. The bioactivities and chemical contents of E. citriodora species, a great value of, Türkiye, were determined, bringing new natural products to organic chemistry. As a result of the study, new bioactive extracts would be obtained and thus, they can effectively reveal the potential of new business opportunities. Since methanol extract is effective against incurable diseases such as Alzheimer's and diabetes, it will also be possible to develop therapeutics of such diseases by investigating the advanced chemistry and in vivo activities of the extracts with new projects.

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Section: Hplc-dad Analysismentioning

confidence: 99%

“…The column temperature was set at 35 ºC. The chromatographic separation was performed on a C18 (5 μm, 4.6 mm x 250 mm) reverse phase column and Inertsil C18 guard column (Tokul-Ölmez et al, 2020).…”

Section: Hplc-dad Analysismentioning

confidence: 99%

Chemical composition and biological activities of essential oils and extract of Eucalyptus citriodora Hook

Şahin,

Cakır,

Sıcak

et al. 2024

International Journal of Secondary Metabolite

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“…The chemical constituents of sample extract were determined by the reverse-phase HPLC-DAD system using a validated method against 27 standards (Tokul-Ölmez et al 2020). The ODS-3 column (Inertsil, 150 mm × 4.0 mm i.d, 4 µm film thickness) was used to separate the compounds.…”

Section: Quantitative Analysis Of Phenolic Compounds By Hplc-dadmentioning

confidence: 99%

Assessment of in vitro activities and chemical profiling of Senecio hoggariensis growing in Algerian Sahara

et al. 2022

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Abstract. Arab Y, Sahin B, Ceylan O, Zellagui A, Olmez OT, Kucukaydin S, Tamfu AN, Ozturk M, Gherraf N. 2022. Assessment of in vitro activities and chemical profiling of Senecio hoggariensis growing in Algerian Sahara. Biodiversitas 23: 3498-3506. The in vitro antioxidant, anticholinesterase, tyrosinase inhibitory, antibiofilm, and anti-quorum sensing activities of the ethyl acetate extract of Senecio hoggariensis,growing in Algerian Sahara, were studied along with its chemical constituents using HPLC-DAD. The chromatographic analysisunveiled seven phenolic compounds, including p-coumaric acid as a major component. Additionally, the extract showed moderate DPPH radical scavenging activity, compared to known standards. At 200 ?g/mL, the extract disclosed equitable acetylcholinesterase (AChE), butyryl-cholinesterase (BChE) and tyrosinase inhibition rates with respective values of 37.01±1.48%, 18.87±4.18% and 45.99±1.81%. Likewise, the extract exhibited a good antibiofilm activity against Candida albicans ATCC 10239 biofilm production with an inhibition ratio of 59.56±0.40%, at 50µg/mL. The anti-quorum sensing by QS-regulated violacein pigment production inhibition test was determined using Chromobacterium violaceum CV026 and CV12472. The swarming motility inhibition assay was determined using Pseudomonas aeruginosa PA01. It is evident from the findings that Senecio hoggariensis could be considered potential antioxidant, anti-QS, and antibiofilm compounds. However, the origin of anti-biofilm and anti-quorum sensing activities of the ethyl acetate extract could be revealed by further studies on the mechanism of action of active compounds that can be isolated via activity-guided fractionation.

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“…In this study, twenty-four tinctures, which may present natural urease inhibitor potential, were prepared in various plant/solvent ratios at different percentages of ethanol/water mixtures from the leaves of the endemic L. orientalis. The phenolic content of each L. orientalis leaf tincture is determined by HPLC-DAD [5]. The urease inhibitory activity of all tinctures was defined according to the Weatherburn method.…”

mentioning

confidence: 99%

Liquidambar orientalis Leaf Tincture: Exploring of Urease Inhibition Activity and Determination of Chemical Components by HPLC-DAD

Sıcak,

Akın Ekmekçioğlu,

Çam

et al. 2024

Rec. Agric. Food. Chem

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Rapid and easy method for simultaneous measurement of widespread 27 compounds in natural products and foods

Cited by 10 publications

References 0 publications

Chemical composition and biological activities of essential oils and extract of Eucalyptus citriodora Hook

Chemical composition and biological activities of essential oils and extract of Eucalyptus citriodora Hook

Assessment of in vitro activities and chemical profiling of Senecio hoggariensis growing in Algerian Sahara

Liquidambar orientalis Leaf Tincture: Exploring of Urease Inhibition Activity and Determination of Chemical Components by HPLC-DAD

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